spindle cells

What is a spindle cell proliferation?

Spindle cell proliferation is a term pathologists use to describe the growth or increase in the number of spindle-shaped cells seen under the microscope. Spindle-shaped cells are long and thin, resembling the shape of a spindle used in weaving, with tapered ends and elongated nuclei. This term is not a final diagnosis but rather a …
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What is a spindle cell lesion?

A spindle cell lesion is a descriptive term used by pathologists to describe a tissue sample containing spindle-shaped cells. These are cells that are longer than they are wide and resemble elongated ovals, thin cigars, or grains of rice when viewed under the microscope. Spindle-shaped cells are normally found in many connective tissues, including muscle, …
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What is a myofibroblastic lesion/proliferation?

A myofibroblastic lesion (also called a myofibroblastic proliferation) is a descriptive term used when a tissue sample contains an increased number of myofibroblasts. Myofibroblasts are specialized cells that share features of fibroblasts (cells that make connective tissue) and muscle cells (cells that can contract). Myofibroblasts normally appear during wound healing and tissue repair, where they …
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What is a malignant spindle cell neoplasm?

A malignant spindle cell neoplasm is a type of cancer made up of spindle-shaped cells. Under the microscope, these cells look long and narrow, similar to the shape of a spindle (a pointed rod used for spinning thread). This diagnosis describes how the cells look under the microscope but does not identify the exact type …
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What is a spindle cell neoplasm?

A spindle cell neoplasm is a tumour made up of spindle-shaped cells, which are cells that are longer than they are wide. Under the microscope, these cells look like elongated ovals or grains of rice. The term spindle cell neoplasm describes how the cells look, not the exact type of tumour. Many different tumours contain …
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Spindle Cells: Definition

In pathology, the term spindle cells is used to describe cells that are longer than they are wide. They are found both in normal, healthy tissue and in tumours. The most common type of normal spindle cell is called a fibroblast. Fibroblasts are support cells that are found in a type of connective tissue called …
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Sarcomatoid: Definition

The term “sarcomatoid” describes cancer cells that resemble those typically found in sarcomas. Sarcomas are cancers that develop from connective tissues like bones, muscles, fat, or blood vessels. Sarcomatoid cells are long, thin, and have pointed ends, giving them a spindle-shaped appearance. Pathologists often use the term sarcomatoid to indicate that these cells have a …
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