TMB

PD-L1 and Tumour Mutational Burden (TMB) in Melanoma

Melanoma is a type of skin cancer that develops from melanocytes, the cells that give skin its color. When melanoma has spread beyond the skin, one of the most effective treatment approaches is immunotherapy, a group of drugs that help the body’s immune system find and attack cancer cells. Two biomarkers can indicate how likely …
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Tumour Mutational Burden

Tumour mutational burden — usually abbreviated as TMB — is a measurement of how many genetic mutations are present in a tumour. The more mutations a cancer carries, the more it tends to look different from normal cells to the immune system. Because immunotherapy drugs work by helping the immune system find and attack cancer, …
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