Pathology dictionary -
Stroma is the tissue just below the surface of an organ. It is a type of connective tissue that helps hold the other parts of the organ together.
Stroma is made up of cells that give the tissue its strength and shape, blood vessels that bring nutrients to the tissue, and lymphatic channels that remove excess fluid and waste.
The way stroma looks when viewed under the microscope changes in response to injury or or cancer. Desmoplasia is a word used to describe the look of the stroma after cancer cells have entered the tissue. The movement of cancer cells into a tissue is called invasion and pathologists look for desmoplasia when trying to decide if a tumour is benign or malignant.