Osteoclast-like giant cells are very large cells with many nuclei that look like osteoclasts, the cells that normally break down bone. Despite the name, they can be found both inside and outside of bone. They are a type of multinucleated giant cell. Osteoclast-like giant cells are a description of what the pathologist saw under the …
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Definition: Multinucleated giant cells are large cells that contain multiple nuclei. These cells are formed by the fusion of smaller cells, typically macrophages, which are immune cells involved in the body’s response to infection, inflammation, or foreign substances. Multinucleated giant cells are commonly seen in various inflammatory conditions and certain types of tumours. What do …
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A tenosynovial giant cell tumor is a noncancerous tumor that develops from the synovium. The synovium is the thin lining of joints, of the sheaths that surround tendons, and of the small fluid-filled sacs called bursae. The form that develops along a tendon, most often in a finger, is still widely called a giant cell …
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Giant cell tumor of bone is a tumor that develops inside a bone, usually near a joint. It is named for the very large cells with many nuclei that are found throughout the tumor. Most giant cell tumors of bone are not cancer, and they rarely spread to other parts of the body. They can, …
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