Human herpesvirus-8 (HHV-8), also known as Kaposi sarcoma-associated herpesvirus (KSHV), is a virus that belongs to the herpesvirus family. Like other herpesviruses, HHV-8 can remain dormant in the body for a prolonged period after the initial infection. Most healthy individuals infected with HHV-8 never develop symptoms or health problems. However, in some people—especially those with …
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Castleman disease is a rare condition that affects the lymph nodes and the immune system. It involves abnormal growth and inflammation of lymph nodes, leading to various health issues depending on the subtype and extent of involvement. There are different types of Castleman disease, each with distinct characteristics, causes, and clinical outcomes. What are the …
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HHV8-associated multicentric Castleman disease (also called KSHV/HHV8-associated multicentric Castleman disease) is a condition in which the immune system creates a large number of abnormal cells called plasmablasts, due to infection by a virus known as human herpesvirus-8 (HHV8). This leads to enlarged lymph nodes, inflammation throughout the body, and systemic symptoms, such as fever and …
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What is Kaposi sarcoma? Kaposi Sarcoma (KS) is a type of cancer made up of abnormal blood vessels. It is part of a group of cancers called sarcomas. Most of these tumours start in the skin and it is not uncommon for a person to have more than one tumour. Kaposi sarcoma can also develop inside …
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