The term lymphoproliferative disease (LPD) describes a group of conditions in which lymphocytes—a type of white blood cell that helps fight infections—grow or multiply beyond normal levels. Lymphocytes include B cells, T cells, and natural killer (NK) cells. These cells normally protect the body by recognizing and destroying viruses, bacteria, and abnormal cells. In a …
Read More »
Hallmark cells are a distinctive type of abnormal cell seen under the microscope in a cancer called anaplastic large cell lymphoma (ALCL). These cells are a clue that helps pathologists recognize and diagnose this disease. What do hallmark cells look like? Hallmark cells are large and have a very characteristic appearance. Their nuclei, which are …
Read More »
Mastocytosis is a rare group of conditions characterized by an abnormal buildup of mast cells in various parts of the body. Mast cells are a type of immune cell that plays a crucial role in allergic reactions and inflammation. Normally, mast cells help protect your body from infections, but in mastocytosis, these cells become overactive …
Read More »
Sézary syndrome is a rare type of cancer involving specific white blood cells called T cells. Normally, T cells help fight infections and diseases. In Sézary syndrome, these cells become cancerous and multiply out of control. The cancerous T cells, known as Sézary cells, exhibit a unique, folded appearance under the microscope. These abnormal cells …
Read More »
Lymphoplasmacytic lymphoma is a slow growing type of blood cancer involving abnormal immune cells called lymphocytes and plasma cells. These cells typically build up in the bone marrow and occasionally in lymph nodes, the spleen, or other body parts. This abnormal buildup interferes with the body’s ability to produce healthy blood cells. When lymphoplasmacytic lymphoma …
Read More »
This article will help you understand your pathology report for CD30 positive T cell lymphoproliferative disorder. Each section explains an important aspect of the diagnosis and what it means for you. What is primary cutaneous CD30 positive T cell lymphoproliferative disorder? Primary cutaneous CD30 positive T cell lymphoproliferative disorder describes a group of immune system …
Read More »
This article is designed to help you understand your pathology report for CD10 positive B cell lymphoma. Each section explains an important aspect of the diagnosis and what it means for you. What is CD10 positive B cell lymphoma? CD10 positive B cell lymphoma describes a group of immune system cancers involving B cells that …
Read More »
This article is designed to help you understand your pathology report for primary cutaneous anaplastic large cell lymphoma. Each section explains an important aspect of the diagnosis and what it means for you. What is primary cutaneous anaplastic large cell lymphoma? Primary cutaneous anaplastic large cell lymphoma is a type of cancer that develops in …
Read More »
Angioimmunoblastic T-cell lymphoma (AITL) is a rare and aggressive form of lymphoma that affects the immune system. It develops from T cells, a type of white blood cell that normally helps regulate the immune response. This type of lymphoma typically begins in the lymph nodes but can also affect other parts of the body, including …
Read More »
Richter transformation (also known as Richter syndrome) refers to the development of a more aggressive type of cancer in a person who already has a specific type of blood cancer called chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). In most cases, the cancer transforms into a fast-growing type of non-Hodgkin lymphoma called diffuse …
Read More »
