Primary cutaneous follicle centre lymphoma is a type of cancer called a lymphoma that starts in the skin. It develops from B cells, a type of white blood cell that normally helps the immune system fight infection. The word “primary” means the lymphoma begins in the skin rather than spreading there from elsewhere, and at …
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Mycosis fungoides is a type of cancer called lymphoma that starts in the skin. A lymphoma is a cancer of lymphocytes, the white blood cells that help protect the body from infection. In mycosis fungoides, the cancerous cells are a type of lymphocyte called T cells, which build up in the skin and cause rashes, …
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Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is a rare, slow-growing blood cancer that starts in B cells — the white blood cells that help the body fight infections. It belongs to the Hodgkin lymphoma family but differs fundamentally from the more common type, classic Hodgkin lymphoma, in its cell biology, behavior, and treatment. Compared with classic …
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Reed-Sternberg cells are a specific type of abnormal cell found in certain cancers. These cells are large, with a distinctive appearance under the microscope, and they play an important role in the diagnosis of a cancer called Hodgkin lymphoma. Reed-Sternberg cells are believed to be derived from a white blood cell type known as a …
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Classic Hodgkin lymphoma is a type of cancer that starts in the lymph nodes — small bean-shaped glands distributed throughout the body that are part of the immune system. It is defined by the presence of distinctive abnormal cells called Reed-Sternberg cells, which are much larger than normal immune cells and have a characteristic appearance …
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The Hans algorithm is a tool used by pathologists to classify diffuse large B cell lymphoma (DLBCL) into different subtypes based on the expression of specific proteins in the cancer cells. DLBCL is the most common type of non-Hodgkin lymphoma, and it can be divided into two main subtypes: germinal center B-cell-like (GCB) and activated …
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B-lymphoblastic lymphoma (B-LBL) is a fast-growing type of non-Hodgkin lymphoma that starts from immature B cells, a type of white blood cell that normally helps the body fight infection. It is closely related to B-cell acute lymphoblastic leukemia (B-ALL). The two conditions consist of the same type of cancer cell and differ mainly in where …
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Lymphoblastic lymphoma is an aggressive cancer of the immune system that starts in immature lymphocytes called lymphoblasts. Lymphoblasts are the earliest, most immature form of lymphocytes — the white blood cells that normally mature into either B cells (which make antibodies) or T cells (which coordinate immune responses and kill infected cells). In lymphoblastic lymphoma, …
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High-grade B cell lymphoma with MYC and BCL2 rearrangements — also called diffuse large B cell lymphoma (DLBCL) with MYC and BCL2 rearrangements, or informally “double-hit lymphoma” — is an aggressive blood cancer that starts in B cells. These white blood cells help the body fight infections. The name refers to two specific genes, MYC …
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High grade B cell lymphoma NOS (HGBL NOS) is a type of cancer that starts in the white blood cells called B cells. These cells are part of the immune system and help protect your body from infections and diseases. “High grade” means that this type of cancer is likely to grow and spread quickly …
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