Lynch syndrome

MLH1

MLH1 is a gene that produces a protein involved in DNA repair, specifically in a process called mismatch repair. This protein works closely with other mismatch repair proteins, including PMS2, MSH2, and MSH6, to detect and fix small errors that occur when DNA is copied in dividing cells. Together, these proteins play an important role …
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Medullary carcinoma of the colon

Medullary carcinoma is a rare type of colon cancer. It is considered a subtype of adenocarcinoma. Compared to other types of colon cancer, medullary carcinoma is associated with a good prognosis. Despite their similar names, medullary carcinoma of the colon is not related to medullary carcinoma of the thyroid gland. This article will help you …
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Lynch syndrome

What is Lynch syndrome? Lynch syndrome is an inherited condition associated with an increased risk for developing several different types of cancer. It is caused by a genetic change that leads to the loss of a specialized chemical called a mismatch repair protein. Another name for this syndrome is hereditary nonpolyposis colorectal cancer (HNPCC). The …
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Clear cell carcinoma of the ovary

What is clear cell carcinoma of the ovary? Clear cell carcinoma is a type of ovarian cancer. Most clear cell carcinomas are associated with a condition called endometriosis. Endometriosis is the presence of endometrial tissue (which is normally found in the uterus) outside of the uterus and the ovary is a common location to find …
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Endometrioid carcinoma of the ovary

What is endometrioid carcinoma of the ovary? Endometrioid carcinoma is a type of ovarian cancer. Most endometrioid carcinomas are associated with a condition called endometriosis. Endometriosis is the presence of endometrial tissue (which is normally found in the uterus) outside of the uterus and the ovary is a common location to find endometriosis. About 1% …
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