Metastasis is a term used in pathology to describe the process by which cancer spreads from where it first started (the primary site) to other body parts. When cancer cells break away from the original tumor, they can travel through the bloodstream or the lymphatic system (a network of vessels and nodes that helps fight …
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Metastatic adenocarcinoma refers to cancer that has spread from its original (primary) site to other parts of the body. The term adenocarcinoma specifically refers to a type of cancer made up of glandular cells, which are the cells found inside most internal organs. For example, if someone has metastatic adenocarcinoma of the breast, it means …
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Metastatic carcinoma refers to cancer that has spread from its original (primary) site to other parts of the body. The term carcinoma specifically refers to a type of cancer that begins in the epithelial cells, which line the organs and tissues of the body. For example, if someone has metastatic carcinoma of the breast, it …
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In pathology, extranodal extension (ENE) refers to the spread of tumour cells beyond the lymph node capsule into the surrounding tissues. This process is observed in various types of cancers that have metastasized to lymph nodes. ENE is considered a marker of aggressive disease and can significantly impact the staging, prognosis, and treatment strategy for …
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In transit metastasis is a term used to describe cancer that has spread beyond the original tumour but has not yet reached the lymph nodes or distant organs. Instead, the cancer cells travel through small lymphatic vessels and form new tumours between the primary tumour and the nearest lymph nodes. This type of spread is …
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A tumour deposit is a group of cancer cells that have spread from the primary tumour (the location where the tumour started) to another tissue or organ in the body. A tumour deposit can be found close to the primary tumour or in other organs and body sites far from the original tumour. When a …
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