notocord

Brachyury: Definition

Brachyury is a protein that helps control how the body develops before birth. It is made by the notochord, a rod of cells in the early embryo that guides the formation of the spine. Pathologists test for brachyury to help diagnose chordoma, a rare cancer that develops from leftover notochord cells. The gene that makes …
Read More »

Chordoma: Understanding Your Pathology Report

Chordoma is a rare, slow-growing bone cancer. It develops from cells left over from the notochord, a structure that guides spine formation before birth. The notochord normally disappears as the spine forms, but small groups of its cells can remain inside the bones of the spine and skull. Chordoma develops from these leftover cells. Chordomas …
Read More »

A+ A A-