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What is plasmacytoid?

In pathology, cells are described as plasmacytoid if they are round and if the nucleus (the part of the cell that holds the genetic material) is located to the side of the side. Pathologists often describe the location of the nucleus as eccentric or peripheral. These cells are described as plasmacytoid because they look like …
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Epithelioid Cells: Definition

In pathology, cells are described as epithelioid if they are round, have lots of cytoplasm (the material found inside the body of the cell), and have a round to oval-shaped nucleus (the part of the cell that holds the genetic material). They are called epithelioid because they look like epithelial cells – specialized cells found …
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Anal Intraepithelial Neoplasia (AIN): Understanding Your Pathology Report

Anal intraepithelial neoplasia (AIN) is a precancerous condition that affects the cells lining the anus and anal canal. In this condition, the surface cells show abnormal changes, but they have not spread into deeper tissues, which means it is not cancer. However, some cases can progress over time to squamous cell carcinoma of the anus. …
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E-cadherin: Definition

E-cadherin (also called cadherin-1) is a protein found on the surface of most epithelial cells. Epithelial cells are the cells that line many surfaces in the body, including the skin, glands, and the inside of organs such as the breast, stomach, and colon. E-cadherin helps these cells stick together and maintain their structure and organization. …
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Invasive Mammary Carcinoma: Understanding Your Pathology Report

Invasive mammary carcinoma is a general term used to describe a cancer that has grown into the breast tissue but has not yet been sorted into a more specific type of breast cancer. It is often a starting point: after further examination and testing, most invasive mammary carcinomas are reclassified as invasive ductal carcinoma (also …
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Acute Cholecystitis: Understanding Your Pathology Report

Acute cholecystitis refers to the sudden and active inflammation of the gallbladder. The gallbladder is a small, pear-shaped organ located just beneath the liver in the upper right side of the abdomen. Inflammation happens when the gallbladder wall becomes swollen and irritated, usually because something is blocking the normal flow of bile. What is the …
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Erosive Esophagitis: Understanding Your Pathology Report

Erosive esophagitis means that the lining of the esophagus, the muscular tube that carries food and liquid from the mouth to the stomach, is inflamed and has been worn away in places. The esophagus is lined by squamous cells, which form a protective surface layer called the epithelium. When injury damages this layer faster than …
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Candida Esophagitis: Understanding Your Pathology Report

Candida esophagitis is an infection of the esophagus, the muscular tube that carries food and liquid from the mouth to the stomach, caused by a yeast called Candida. The infection produces inflammation and damage to the lining of the esophagus. It is also called esophageal candidiasis or esophageal thrush, and it is the most common …
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Herpes Esophagitis: Understanding Your Pathology Report

Herpes esophagitis is an infection of the esophagus, the muscular tube that carries food and liquid from the mouth to the stomach, caused by the herpes simplex virus (HSV). The infection destroys cells in the surface lining and produces small ulcers, which makes swallowing painful. It is also called herpes simplex esophagitis or HSV esophagitis. …
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