July 31, 2023
Cardiac mucosa is a thin layer of tissue that covers the inside of the first part of the stomach. It is normal to find cardiac mucosa where the esophagus connects with the stomach. This area is called the gastroesophageal junction.
Cardiac mucosa is made up of glands that secrete mucus onto the inside surface of the stomach. The mucus helps protect the tissue from the strong acids produced in the body of the stomach.
Cardiac mucosa with chronic inflammation means that specialized immune cells, specifically lymphocytes and plasma cells were seen on the inside surface of the stomach when the tissue was examined under the microscope. Common causes of chronic inflammation in this part of the stomach include infection with Helicobacter pylori, nonsteroidal anti-inflammatory drugs (NSAIDs), and gastroesophageal reflux disease (GERD).
It is normal to find cardiac type gastric mucosa in the esophagus. When examined under the microscope the cardiac type mucosa within the esophagus looks very similar to cardiac mucosa in the stomach.
Cardiac mucosa with intestinal metaplasia means that some of the cells on the inside of the stomach have changed so that they look and behave more like cells normally found on the inside of the small intestine. Common causes of intestinal metaplasia involving cardiac mucosa include long-standing infection with Helicobacter pylori, nonsteroidal anti-inflammatory drugs (NSAIDs), and gastroesophageal reflux disease (GERD).