Pemphigus is a group of rare autoimmune diseases that affect the skin and mucous membranes (the moist surfaces inside your mouth, nose, throat, and genitals). The outer layer of these tissues is made of keratinocytes, which are flat cells arranged like tiles on a roof. In pemphigus, the immune system produces antibodies that target specific …
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DIF stands for direct immunofluorescence. It is a test that pathologists perform to look for specific proteins in a tissue sample. Unlike most tissue samples, which are examined using normal light, DIF tissue samples are examined using fluorescent light. This makes it easier for pathologists to see exactly where in the tissue sample the proteins …
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Direct immunofluorescence (DIF) is a specialized laboratory test pathologists use to identify specific proteins within a tissue sample. This test involves using antibodies attached to a fluorescent dye that glows brightly under a special microscope. By lighting up these proteins, DIF helps pathologists see their location and pattern within the tissue. Why is direct immunofluorescence …
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