An immunostain is a specialized laboratory test that pathologists use to identify specific proteins in a tissue sample. The test is performed using a technique called immunohistochemistry (IHC). In this process, antibodies are designed to attach to a particular protein in the cells of the sample. Once the antibody binds, it becomes visible under the …
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Cytokeratin 20 (CK20) is a protein made by epithelial cells in the colon and urinary tract. It is also made by Merkle cells in the skin. This type of protein is also made by most benign (noncancerous) and malignant (cancerous) tumours that start in the colon and urinary tract and in a type of skin …
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Cytokeratin 7 (CK7) is a protein made by epithelial cells in the thyroid gland, lungs, thymus, female reproductive organs, upper digestive tract, and head and neck. This type of protein is also made by most benign (noncancerous) and malignant (cancerous) tumours that start in these organ systems. After CK7 is made, it is held in …
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Immunohistochemistry (IHC) is a laboratory test that detects specific proteins in cells within a tissue sample. It uses antibodies that bind to a specific protein and then turn it a visible color, usually brown, under the microscope. Pathologists use it to identify cell types in a sample and look for features that help guide treatment. …
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