Fumarate hydratase-deficient renal cell carcinoma (often called FH-deficient RCC) is a rare type of kidney cancer. It develops due to mutations (changes) in a gene called fumarate hydratase (FH). FH is important for normal cell metabolism. Changes in this gene lead to the formation of a tumour with specific microscopic features. This tumour often behaves …
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Tubulocystic renal cell carcinoma (TcRCC) is a rare type of kidney cancer. It begins in very small tubes (tubules) and cysts within the kidney. A cyst is a small sac filled with fluid. These tumours typically have a cystic appearance, meaning they contain multiple small cysts. Tubulocystic renal cell carcinoma is usually a slow-growing tumour …
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A papillary adenoma is a small, non-cancerous (benign) kidney tumour. It arises from tiny tubes inside the kidney called tubules. Papillary adenomas typically measure less than 15 millimeters (about 0.6 inches) in size. They often exhibit a pattern of growth described as papillary, meaning they develop in small, finger-like projections. Sometimes the growth pattern is …
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Background: Angiomyolipoma (AML) is a benign (non-cancerous) tumour made up of a combination of adipose tissue (fat), smooth muscle, and blood vessels. This type of tumour is most commonly found in the kidney, although it can also be found in the liver and pancreas. What causes angiomyolipoma? Most angiomyolipomas contain a genetic alteration that renders …
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What is Xp11 translocation renal cell carcinoma? Xp11 translocation renal cell carcinoma (RCC) is a type of kidney cancer. It is called ‘Xp11 translocation’ because the tumour cells contain a genetic alteration involving the TFE3 gene which is located in the p11 region of chromosome X. Another name for this type of cancer is TFE3-rearranged …
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What is TFE3-rearranged renal cell carcinoma? TFE3-rearranged renal cell carcinoma (RCC) is a type of kidney cancer. It is called ‘TFE3-rearranged’ because the tumour cells contain a genetic alteration involving the TFE3 gene. Another name for this type of cancer is Xp11 translocation renal cell carcinoma. What causes TFE3-rearranged renal cell carcinoma? This type of …
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An oncocytoma is a non-cancerous (benign) tumour found in the kidney. The tumour is composed of large, pink cells known as oncocytes. Oncocytomas usually grow slowly and rarely cause serious health problems. What are the symptoms of oncocytoma? Most oncocytomas in the kidney do not cause noticeable symptoms. They are typically discovered accidentally during imaging …
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Papillary renal cell carcinoma is a type of kidney cancer. It develops from tiny tubes inside the kidney called tubules. It is the second most common type of kidney cancer found in adults. The outlook for papillary renal cell carcinoma can vary significantly depending on the specific type of tumour, its grade, and the extent …
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Clear cell renal cell carcinoma is a type of kidney cancer. It develops from tiny tubes inside the kidney called tubules. Clear cell renal cell carcinoma is the most common type of kidney cancer found in adults. Many clear cell renal cell carcinomas grow slowly and have a good outlook. However, some tumors may behave …
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Chromophobe renal cell carcinoma is a type of kidney cancer. It develops from very small tubes (tubules) within the kidneys. It is the third most common type of kidney cancer in adults. Most people with chromophobe renal cell carcinoma have a very good prognosis. However, the outlook may change if special types of aggressive cells—called …
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