In pathology, the term basal lymphoplasmacytosis is used to describe large groups of immune cells called lymphocytes and plasma cells within the layer of tissue that covers the inside of the colon. Because large groups of lymphocytes and plasma cells are not normally seen in the colon, this change is used to support the diagnosis …
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Crypt distortion describes changes that affect the size, shape, and number of crypts in the colon. Crypts are tiny, specialized glands lining the inner surface of the colon. Normally, these crypts are uniform, straight, and evenly spaced, resembling a neat row of test tubes. When crypt distortion occurs, these structures become irregular, shorter, fewer in …
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Fluorescence in situ hybridization (FISH) is a laboratory test used in pathology to detect and localize the presence or absence of specific DNA sequences on chromosomes. It works by using fluorescent probes that bind to only those parts of the chromosome that match or are complementary to the probe. It is commonly used in the …
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Myelodysplastic syndrome (MDS) is a group of blood cancers that affect the bone marrow, the spongy tissue inside bones where new blood cells are made. In MDS, the bone marrow produces blood cells that do not develop or function properly, so many are destroyed before they can do their job. As a result, people with …
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In pathology, an excision refers to the surgical removal of a piece of tissue from the body. This procedure is commonly performed to remove abnormal tissue, such as a tumor or an area of infection, and can be done for both diagnostic and therapeutic purposes. In a diagnostic context, an excision may be carried out …
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A well differentiated neuroendocrine tumor is a type of pancreatic cancer that starts from neuroendocrine cells in the hormone-producing (endocrine) part of the pancreas. These cells are found in small, round clusters called islets of Langerhans, and they produce hormones such as insulin and glucagon that help regulate body functions like blood sugar levels. “Well …
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What does chronic gastritis mean? Chronic gastritis means inflammation of the lining on the inside of the stomach. The inflammation prevents the stomach from functioning normally by damaging the specialized foveolar cells that cover the inside surface of the stomach. What are the symptoms of chronic gastritis? The most common symptoms of chronic gastritis are …
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Suspicious for follicular neoplasm is a preliminary diagnosis used by pathologists to describe a growth in the thyroid gland made up of cells that look like the follicular cells of the thyroid. This term is most often used after a procedure called a fine-needle aspiration biopsy (FNAB), in which a small sample of cells is …
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Follicular neoplasm is a preliminary diagnosis used by pathologists to describe a growth in the thyroid gland made up of cells that look like the follicular cells of the thyroid. This term is most often used after a procedure called a fine-needle aspiration biopsy (FNAB), in which a small sample of cells is taken from …
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Fibrocystic change is a non-cancerous (benign) condition of the breast that includes several related changes that often occur together. These changes include cysts, fibrosis, apocrine metaplasia, and adenosis. Fibrocystic change is very common and is seen in up to 60% of women of reproductive age. It can affect one or both breasts and may cause …
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