Reactive gastropathy, also known as chemical gastropathy, is a condition in which the stomach’s lining becomes damaged after exposure to substances not normally present in the stomach. These substances may include bile, alcohol, or non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or aspirin. The damage causes changes in the cells that normally protect the stomach, …
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Chemical gastropathy is a condition that develops when the lining of the stomach is damaged by irritating substances such as bile, non-steroidal anti-inflammatory drugs (NSAIDs), or alcohol. Another name for this condition is reactive gastropathy. Under normal conditions, the inside of the stomach is lined by special foveolar cells that produce mucus, a protective layer …
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What is peptic duodenitis? Peptic duodenitis is an injury associated with inflammation in a part of the small intestinal called the duodenum. It is caused by increased acid production in the stomach. The extra acid spills into the duodenum where it damages the cells in the mucosa. The damage causes abdominal pain which is worse …
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What is a pancreatic mucinous cystic neoplasm? Mucinous cystic neoplasm is a non-cancerous type of pancreatic tumour. This tumour occurs most often in women around 50 years of age. It is usually located at the end of the pancreas in the area called the tail but may also be found less often in the head …
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Human papillomavirus (HPV) is a very common virus transmitted through sexual contact. There are over 100 different types of HPV, and some are more likely than others to cause health problems, including cancer. HPV infects specific cells called squamous cells, which are normally found in areas such as the skin, mouth, throat, cervix, penis, and …
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Hematoxylin and eosin (H&E) are two special dyes that pathologists use to stain tissue samples, allowing them to be examined under a microscope. When tissue is removed from the body during a biopsy or surgery, it is processed and placed on glass slides for microscopic evaluation. However, without staining, the tissue appears nearly colorless, and the …
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A crypt abscess is a collection of specialized immune cells called neutrophils found inside the crypts of the colon. Crypts are small, tube-shaped glands that line the inside of the colon and help it function properly. When neutrophils accumulate within these crypts, it indicates acute (recent onset or active) inflammation. This condition is commonly observed …
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Cryptitis is a word pathologists use to describe inflammation involving the tissue inside the colon. The inflammation is caused by specialized immune cells called neutrophils. It is an example of acute inflammation and is often seen in a condition called active colitis. What does cryptitis look like under the microscope? The tissue on the inside …
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In pathology, the term basal lymphoplasmacytosis is used to describe large groups of immune cells called lymphocytes and plasma cells within the layer of tissue that covers the inside of the colon. Because large groups of lymphocytes and plasma cells are not normally seen in the colon, this change is used to support the diagnosis …
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Crypt distortion describes changes that affect the size, shape, and number of crypts in the colon. Crypts are tiny, specialized glands lining the inner surface of the colon. Normally, these crypts are uniform, straight, and evenly spaced, resembling a neat row of test tubes. When crypt distortion occurs, these structures become irregular, shorter, fewer in …
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