Endometrial hyperplasia without atypia is a noncancerous (benign) condition in which the lining of the uterus becomes thicker than normal. The lining is called the endometrium. In this condition, the endometrial glands grow and multiply more than they should, so they become crowded together. The words “without atypia” carry most of the meaning. They tell …
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A hyperplastic polyp is a common benign (non-cancerous) growth that develops on the inner lining of the large intestine, which includes the colon and the rectum. Hyperplastic polyps are not precancerous. They do not contain the abnormal cells that lead to cancer, and for most people, finding one does not change the colorectal cancer screening …
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Usual ductal hyperplasia (UDH) is a non-cancerous (benign) condition commonly found in breast biopsies. It describes an increase in the number of normal-looking cells within the small ducts of the breast, typically in a region of the breast known as the terminal duct lobular unit. These cells multiply in a disorganized manner but do not …
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HPV-associated squamous cell carcinoma is the most common type of cervical cancer. It develops from squamous cells, the flat cells that line the outer surface of the cervix, following persistent infection with high-risk types of human papillomavirus (HPV). Most cases develop slowly over many years from a precancerous condition called high-grade squamous intraepithelial lesion (HSIL). …
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High grade squamous intraepithelial lesion (HSIL) of the vulva is a precancerous condition caused by persistent infection with human papillomavirus (HPV). It is made up of abnormal squamous cells that are confined to the top layer of the vulvar skin (the epidermis). HSIL can also occur on the mucosal surfaces near the vaginal opening, where …
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Low grade squamous intraepithelial lesion (LSIL) in the vagina is an abnormal growth caused by infection with human papillomavirus (HPV). The abnormal growth seen in LSIL is an example of dysplasia. In addition to the vagina, LSIL can also affect the anal canal, vulva, and cervix. In men, LSIL can affect the penis and scrotum. …
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Low grade squamous intraepithelial lesion (LSIL) is a precancerous condition of the cervix caused by infection with human papillomavirus (HPV). It is composed of squamous cells infected and altered by the virus. These abnormal cells are usually found in the transformation zone, the part of the cervix where glandular cells are gradually replaced by squamous …
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Papillary renal cell carcinoma is a type of kidney cancer. It starts from the cells that line the tiny tubes inside the kidney called tubules, which filter the blood and make urine. It is the second most common type of kidney cancer in adults, making up about 15 out of every 100 kidney cancers. The …
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Ductal adenocarcinoma is the most common type of pancreatic cancer. It starts from the cells that line the small tubes (ducts) inside the pancreas. These cells normally help carry digestive fluids made by the pancreas into the small intestine. In ductal adenocarcinoma, cells begin to grow abnormally and invade surrounding tissue. Over time, the cancer may spread …
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Merkel cell carcinoma is a rare type of skin cancer. It is a kind of neuroendocrine tumor, meaning it develops from neuroendocrine cells in the skin. Neuroendocrine cells are specialized cells that send signals by releasing chemical messengers in response to nerve activity. Merkel cell carcinoma tends to grow quickly and is more likely to …
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