Mantle cell lymphoma is a type of blood cancer that starts in B cells — the white blood cells that help the body fight infections by producing antibodies. It takes its name from the mantle zone, a ring of B cells that normally surrounds the germinal center within a lymph node, and it is from …
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A plasma cell neoplasm is a group of related diseases that begin when plasma cells, a type of immune cell found in the bone marrow, start growing abnormally. Normal plasma cells make immunoglobulins (antibodies) that help the body fight infections. In a plasma cell neoplasm, one group of plasma cells grows more than it should …
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Diffuse large B cell lymphoma (DLBCL) is the most common type of lymphoma in adults. It is an aggressive cancer that starts in B cells — the white blood cells that normally help the body fight infections. The word “diffuse” refers to how the cancer cells grow in flat, sheet-like areas that spread through the …
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Hodgkin lymphoma is a type of cancer that starts in the immune system, most often in the lymph nodes — the small, bean-shaped glands distributed throughout the body that filter lymph fluid and house immune cells. It is defined by the presence of specific abnormal cells called Reed-Sternberg cells, which can be identified under the …
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Burkitt lymphoma is a rapidly growing blood cancer that starts in B cells — the white blood cells that help the body fight infections. It is classified as a type of non-Hodgkin lymphoma and is defined by a specific genetic change in the MYC gene. This change causes the cancer cells to divide at an …
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Follicular lymphoma is a group of closely related blood cancers that start in B cells — specialized white blood cells that normally help the body fight infection. These cancers are called “follicular” because the abnormal cells grow in round clusters called follicles, resembling the normal structures found inside healthy lymph nodes. Follicular lymphoma is the …
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Background: Undifferentiated pleomorphic sarcoma (UPS) is a rare and aggressive cancer that arises from connective tissues, including muscles, tendons, fat, and fibrous tissues. The term “undifferentiated” indicates that the tumour cells do not resemble normal cells in the body and lack specific differentiation toward a particular tissue type. “Pleomorphic” refers to the varied shapes and …
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What is superficial fibromatosis? Superficial fibromatosis is a non-cancerous tumour made up of a specialized type of connective tissue called fibrous tissue. What are the types of superficial fibromatosis? Palmar fibromatosis Palmar fibromatosis is a type of superficial fibromatosis that affects the palm (inside surface) of the hand. It is also called Dupuytren’s contracture. Palmar …
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Synovial sarcoma is a rare type of soft tissue cancer. Despite its name, it does not usually start from the lining of joints (synovium). Instead, it arises from primitive connective tissue cells that exhibit features of both spindle-shaped cells and epithelial cells. This article explains the pathology report for synovial sarcoma, including how it is …
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Sinonasal undifferentiated carcinoma (SNUC) is a rare, fast-growing cancer that starts from cells that line the inside of the nasal cavity and paranasal sinuses, an area of the body called the sinonasal tract. The paranasal sinuses are air-filled spaces in the bones around the nose. The term “undifferentiated” means the cancer cells are so abnormal …
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