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Contaminant
In pathology, a contaminant refers to tissue or cells that mistakenly become included within a patient’s tissue sample during the laboratory process. Unlike a floater, which accidentally appears only on a microscope slide, a contaminant is embedded directly into the patient’s paraffin tissue block. As a result, contaminants repeatedly appear each time additional slides (recuts) …
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Floater
In pathology, a floater refers to a small piece of tissue or cells seen on a microscope slide that does not belong to the patient’s original specimen. Floaters typically occur by accident during the preparation of slides in the pathology laboratory. For example, they can happen when tiny fragments of tissue from one sample inadvertently …
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Nonviable
In pathology, the term “nonviable” describes tissue or cells that are no longer alive or able to function normally. Nonviable tissue cannot be accurately examined or tested because it has become damaged or has died, meaning pathologists cannot reliably interpret results from it. What could cause a sample to be nonviable? A sample may become …
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Neuroendocrine tumor of the larynx
A neuroendocrine tumor (NET) of the larynx (also known as a well differentiated neuroendocrine tumor) is a rare type of cancer that develops from specialized cells called neuroendocrine cells, which release hormones into the blood in response to signals from the nervous system. These tumors occur in the larynx (voice box), the structure in your …
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Keratinizing
Keratinizing refers to a process in which squamous cells produce and fill up with a protein called keratin. Keratin is a strong, protective substance that helps tissues resist damage and dehydration. As squamous cells become keratinizing, they grow tougher and thicker and lose their ability to function as living cells. Instead, they form a protective …
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Adult T cell leukemia/lymphoma
Adult T cell leukemia/lymphoma (ATLL) is a rare cancer that affects T cells, a type of white blood cell that plays a key role in the immune system. When cancer primarily affects the blood and bone marrow, it is called leukemia, and when it forms a mass in the lymph nodes or other tissues outside …
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Matted lymph nodes
Matted lymph nodes are groups of lymph nodes that have become stuck together, forming a single mass. Lymph nodes are small, bean-shaped structures that are part of the immune system. They help the body fight infections by filtering out harmful substances. Normally, lymph nodes are separate from one another, but in certain conditions, they can …
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Multinucleated giant cells
Definition: Multinucleated giant cells are large cells that contain multiple nuclei. These cells are formed by the fusion of smaller cells, typically macrophages, which are immune cells involved in the body’s response to infection, inflammation, or foreign substances. Multinucleated giant cells are commonly seen in various inflammatory conditions and certain types of tumours. What do …
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Chondroid
In pathology, chondroid refers to tissue that looks and behaves like cartilage. Cartilage is a firm, flexible tissue found in various body parts, such as the joints and respiratory tract. What does chondroid tissue look like under the microscope? Chondroid tissue appears glassy and smooth under the microscope and is made up of cells called …
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