A neuroendocrine tumor (NET) of the larynx (also known as a well differentiated neuroendocrine tumor) is a rare type of cancer that develops from specialized cells called neuroendocrine cells, which release hormones into the blood in response to signals from the nervous system. These tumors occur in the larynx (voice box), the structure in your …
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Keratinizing refers to a process in which squamous cells produce large amounts of a protein called keratin. Keratin is a tough, protective substance that makes tissues more resistant to injury, infection, and dehydration. As squamous cells become keratinizing, they gradually lose their ability to function as living cells. Instead, they form a strong outer layer …
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Adult T-cell leukemia/lymphoma (ATLL) is a rare type of blood cancer that develops in T cells. T cells are a type of white blood cell that plays a key role in the immune system by fighting infections and helping to regulate immune responses. When ATLL mainly affects the blood and bone marrow, it is called …
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Matted lymph nodes are groups of lymph nodes that have become stuck together, forming a single mass. Lymph nodes are small, bean-shaped structures that are part of the immune system. They help the body fight infections by filtering out harmful substances. Normally, lymph nodes are separate from one another, but in certain conditions, they can …
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Definition: Multinucleated giant cells are large cells that contain multiple nuclei. These cells are formed by the fusion of smaller cells, typically macrophages, which are immune cells involved in the body’s response to infection, inflammation, or foreign substances. Multinucleated giant cells are commonly seen in various inflammatory conditions and certain types of tumours. What do …
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In pathology, chondroid refers to tissue that looks and behaves like cartilage. Cartilage is a firm, flexible tissue found in various body parts, such as the joints and respiratory tract. What does chondroid tissue look like under the microscope? Chondroid tissue appears glassy and smooth under the microscope and is made up of cells called …
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Background: An ampullary adenoma is a non-cancerous growth that forms in the ampulla of Vater. The ampulla is a small opening where the bile and pancreatic ducts meet and empty their fluids into a part of the small intestine called the duodenum. These fluids help break down food during digestion. While an adenoma is benign …
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In pathology, the term amorphous is used to describe material that has no clear shape or structure when viewed under a microscope. Unlike normal tissues and cells, which have distinct forms and patterns, amorphous material appears shapeless and unorganized, often as a featureless background or a dense mass with no identifiable cell types. This word …
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Neuroendocrine differentiation is a term pathologists use to describe cells that exhibit features of both nerve cells and hormone-producing cells. These cells are capable of producing, storing, and releasing hormones, much like cells in the nervous and endocrine systems. Neuroendocrine differentiation can be seen in both normal tissues and tumours. When seen in a tumour, …
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In pathology, the term “blastoid” refers to cells that have features resembling immature precursor cells, known as blasts, which are typically found in the bone marrow. These cells are generally considered abnormal and can be indicative of aggressive and rapidly proliferating diseases, often seen in certain types of cancers. Microscopic features of blastoid cells Blastoid …
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