pathology

Blasts: Definition

In pathology, the term “blasts” refers to immature cells in the early stages of development into mature cells. These cells are typically found in the bone marrow, which is part of the normal process of blood cell formation known as hematopoiesis. Blasts can develop into various types of blood cells, such as red blood cells, white …
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Cribriform Morular Thyroid Carcinoma: Understanding Your Pathology Report

Cribriform morular thyroid carcinoma (CMTC) is a rare type of thyroid gland cancer. The thyroid is a butterfly-shaped gland in the neck that produces hormones important for metabolism. Cribriform morular thyroid carcinoma is unique due to its specific appearance under the microscope and its association with certain genetic conditions. What are the symptoms of cribriform …
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Malignant Transformation: Definition

In pathology, the term malignant transformation describes the development of a malignant (cancerous) tumour from a benign (noncancerous) tumour or a precancerous disease. Malignant transformation is important because the cells in the malignant tumour can grow into nearby tissues and metastasize (spread) to distant organs such as lymph nodes and the lungs. Common conditions that …
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Dyskeratotic Cells: Definition

Dyskeratotic cells are squamous cells that have undergone premature or abnormal keratinization, a process by which cells produce and accumulate a protein called keratin. Under microscopic examination, these cells are smaller and pinker than normal squamous cells. Dyskeratotic cells can be seen in a variety of precancerous, cancerous, infectious, and inflammatory conditions. What conditions are …
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Pathologist: Definition

A pathologist is a specialist medical doctor who examines tissues, cells, organs, and bodily fluids to diagnose diseases, determine their nature, and provide information crucial for treatment decisions. Types of pathologists include anatomical pathologists, hematopathologists, neuropathologists, cytopathologists, and forensic pathologists. Pathologists often work in hospitals, laboratories, or academic institutions. Their findings contribute significantly to the …
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Fibroblasts: Definition

Fibroblasts are a type of cell normally found in connective tissue. They play an important role in maintaining the structural framework of tissues and organs in the body. They are one the most common types of cells found in connective tissue and are primarily involved in producing and secreting the extracellular matrix, which provides structural …
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Glandular Cells: Definition

Glandular cells are specialized epithelial cells that form the functional units of most internal organs. They are involved in the production and secretion of substances that aid in the normal activity of the organ. These substances may include enzymes, hormones, mucus, or other products that are released into ducts, surfaces, or the bloodstream for various …
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Endosalpingiosis: Definition

Endosalpingiosis is a condition where tissue similar to that normally found in the fallopian tube is found outside of the fallopian tube. This tissue may be found in various pelvic organs and structures, such as the ovaries, peritoneum (lining of the abdominal cavity), and other pelvic tissues. It can also be found in small immune …
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B-Lymphoblastic Leukemia (B-ALL): Understanding Your Pathology Report

B-lymphoblastic leukemia, also called B-cell acute lymphoblastic leukemia (B-ALL), is a type of blood cancer that starts in the bone marrow (the soft inner part of bones where blood cells are made). In this disease, the bone marrow produces large numbers of immature white blood cells called lymphoblasts. These lymphoblasts come from a type of …
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Fibrovascular Core: Definition

A fibrovascular core is a small microscopic structure made up of fibrous tissue (connective tissue) and blood vessels. These cores are found inside finger-like projections called papillae. Papillae are common features in many types of growths, including both benign (noncancerous) and malignant (cancerous) ones. For example, fibrovascular cores can be seen in benign papillomas, as …
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