Lymphoblasts are immature cells that develop into lymphocytes, a type of white blood cell that is integral to the immune system. They are part of the body’s adaptive immune response, responsible for fighting infections and providing long-term immunity. Where are lymphoblasts normally found? Lymphoblasts are primarily found in the bone marrow, the soft, spongy center …
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ECL cell hyperplasia refers to an increase in the number of enterochromaffin-like (ECL) cells within the stomach lining. ECL cells are neuroendocrine cells that play an important role in the regulation of acid production in the stomach. Where are ECL (enterochromaffin-like) cells normally found, and what do they do? ECL cells are normally found in …
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Intranuclear inclusions are abnormal collections of material found inside the nucleus of a cell. The nucleus is the control center of the cell where the genetic material (DNA) is stored. Under the microscope, intranuclear inclusions appear as small, round, compact areas within the nucleus that look different from the surrounding material because of their color, …
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Goblet cells are large, round, mucin-filled cells found in the body’s mucous membranes. They are responsible for producing mucus. This secretion is a protective lubricant coating the lining of various organs, including parts of your digestive and respiratory systems. Where are goblet cells normally found? Goblet cells are typically located in the linings of your …
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In pathology, rhabdoid describes tumour cells resembling immature muscle cells called rhabdomyoblasts. Although these cells resemble developing muscle cells, they are not actually muscle-related, and tumours with rhabdoid cells typically do not arise from muscle tissue. Instead, “rhabdoid” refers specifically to their appearance under a microscope. Tumours containing rhabdoid cells tend to behave aggressively and …
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Leukemia is a type of cancer that affects the blood and bone marrow, the spongy tissue inside bones where blood cells are made. It is characterized by the rapid production of abnormal white blood cells (WBCs), which are not fully developed and do not function properly. These abnormal cells can accumulate in the blood and …
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In pathology, the term amorphous is used to describe material that has no clear shape or structure when viewed under a microscope. Unlike normal tissues and cells, which have distinct forms and patterns, amorphous material appears shapeless and unorganized, often as a featureless background or a dense mass with no identifiable cell types. This word …
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A collection of eosinophils inside tissue is called an eosinophilic abscess. Eosinophilic abscesses are often seen in areas of infection, especially infections caused by fungi or parasites. If the collection is large enough, it can form a sticky substance called pus. An eosinophilic microabscess is a small group of eosinophils inside tissue. Microabscesses can only …
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Macrophages are a type of white blood cell (WBC) that play an important role in the immune system, particularly in a process called phagocytosis, where they engulf and digest pathogens (viruses and bacteria), dead cells, and cellular debris. They start their life as monocytes, a type of blood cell, that migrate from the blood to …
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The term “peripheral nerve sheath tumour” (PNST) refers to a group of tumours that arise from the nerve sheath, which is the protective covering of the peripheral nerves. These nerves are the ones that extend outside the central nervous system (brain and spinal cord) to the rest of the body. The nerve sheath is made …
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