Intranuclear inclusions are abnormal collections of protein or other material found within the nucleus of a cell. These inclusions appear as rounded, compact masses that are often distinct from the surrounding nuclear material because of their colour, density, or composition. Medical conditions associated with intranuclear inclusions Intranuclear inclusions are associated with various medical conditions, the …
Read More »
Goblet cells are large, round, mucin-filled cells found in the body’s mucous membranes. They are responsible for producing mucus. This secretion is a protective lubricant coating the lining of various organs, including parts of your digestive and respiratory systems. Where are goblet cells normally found? Goblet cells are typically located in the linings of your …
Read More »
In pathology, rhabdoid describes tumour cells resembling immature muscle cells called rhabdomyoblasts. Although these cells resemble developing muscle cells, they are not actually muscle-related, and tumours with rhabdoid cells typically do not arise from muscle tissue. Instead, “rhabdoid” refers specifically to their appearance under a microscope. Tumours containing rhabdoid cells tend to behave aggressively and …
Read More »
Leukemia is a type of cancer that affects the blood and bone marrow, the spongy tissue inside bones where blood cells are made. It is characterized by the rapid production of abnormal white blood cells (WBCs), which are not fully developed and do not function properly. These abnormal cells can accumulate in the blood and …
Read More »
In pathology, the term amorphous is used to describe material that has no clear shape or structure when viewed under a microscope. Unlike normal tissues and cells, which have distinct forms and patterns, amorphous material appears shapeless and unorganized, often as a featureless background or a dense mass with no identifiable cell types. This word …
Read More »
A collection of eosinophils inside tissue is called an eosinophilic abscess. Eosinophilic abscesses are often seen in areas of infection, especially infections caused by fungi or parasites. If the collection is large enough, it can form a sticky substance called pus. An eosinophilic microabscess is a small group of eosinophils inside tissue. Microabscesses can only …
Read More »
Macrophages are a type of white blood cell (WBC) that play an important role in the immune system, particularly in a process called phagocytosis, where they engulf and digest pathogens (viruses and bacteria), dead cells, and cellular debris. They start their life as monocytes, a type of blood cell, that migrate from the blood to …
Read More »
The term “peripheral nerve sheath tumour” (PNST) refers to a group of tumours that arise from the nerve sheath, which is the protective covering of the peripheral nerves. These nerves are the ones that extend outside the central nervous system (brain and spinal cord) to the rest of the body. The nerve sheath is made …
Read More »
In pathology, the term “blastoid” refers to cells that have features resembling immature precursor cells, known as blasts, which are typically found in the bone marrow. These cells are generally considered abnormal and can be indicative of aggressive and rapidly proliferating diseases, often seen in certain types of cancers. Microscopic features of blastoid cells Blastoid …
Read More »
In pathology, the term “blasts” refers to immature cells in the early stages of development into mature cells. These cells are typically found in the bone marrow, which is part of the normal process of blood cell formation known as hematopoiesis. Blasts can develop into various types of blood cells, such as red blood cells, white …
Read More »
