HSIL

What is high grade squamous intraepithelial lesion (HSIL)?

High grade squamous intraepithelial lesion (HSIL) is a precancerous condition caused by infection with human papillomavirus (HPV). It involves abnormal changes in squamous cells, which are flat cells found on the surface of tissues such as the cervix, vagina, vulva, penis, and anal canal. HSIL is primarily caused by high-risk HPV types, especially types 16 …
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What is p16?

p16 is a protein produced by many cells in the body. It plays an important role in regulating how cells grow and divide. Because it helps prevent cells from growing uncontrollably, p16 is known as a tumor suppressor protein. When cells lose control of their growth, it can lead to cancer. Pathologists often test for …
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