HSIL

High grade squamous intraepithelial lesion (HSIL)

High grade squamous intraepithelial lesion (HSIL) is a precancerous disease caused by human papillomavirus (HPV). It is composed of abnormal squamous cells that have been infected and transformed by the virus. There are many types of HPV but most cases of HSIL are caused by the high-risk types 16 and 18. HSIL can involve the …
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High grade squamous intraepithelial lesion of the anus and anal canal

High grade squamous intraepithelial lesion (HSIL) is a precancerous disease caused by human papillomavirus (HPV). It is composed of abnormal squamous cells that have been infected and transformed by the virus. Squamous cells are found in a thin layer of tissue called the epithelium which covers the inside surface of the anus and anal canal. …
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Squamous cell carcinoma of the cervix

Squamous cell carcinoma (SCC), also called invasive squamous cell carcinoma, is the most common type of cervical cancer. The tumour starts from squamous cells normally found in the epithelium on the outside surface of the cervix. SCC of the cervix can be keratinizing (KSCC), non-keratinizing (NKSCC), or basaloid. Keratinizing means that the tumour cells are …
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High grade squamous intraepithelial lesion of the vagina

High grade squamous intraepithelial lesion (HSIL) is a precancerous disease caused by human papillomavirus (HPV). It is composed of abnormal squamous cells that have been infected and transformed by the virus. Squamous cells are found in a thin layer of tissue called the epithelium which covers the inside surface of the vagina. There are many …
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High grade squamous intraepithelial lesion of the vulva

High grade squamous intraepithelial lesion (HSIL) is a precancerous disease caused by human papillomavirus (HPV). It is composed of abnormal squamous cells that have been infected and transformed by the virus. Squamous cells are found in a thin layer of tissue called the epithelium which covers the surface of the vulva. There are many types …
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High grade squamous intraepithelial lesion of the cervix

High grade squamous intraepithelial lesion (HSIL) of the cervix is a precancerous disease caused by human papillomavirus (HPV). It is composed of abnormal squamous cells that have been infected and transformed by the virus. The squamous cells are found in a part of the cervix called the transformation zone. There are many types of HPV …
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Squamous cell carcinoma of the vagina

What is squamous cell carcinoma of the vagina? Squamous cell carcinoma is the most common type of cancer in the vagina. The tumour starts from specialized squamous cells that cover the inside surface of the vagina. What causes squamous cell carcinoma of the vagina? The most common cause of squamous cell carcinoma in the vagina …
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p16

p16 is a protein made by normal cells throughout the body. It can also be made by abnormal cells including some types of cancers. It is a type of protein called a tumour suppressor. This means that the normal role of this protein is to stop the cell from changing into a cancer cell. After …
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