HSIL

Cervix: Squamous cell carcinoma

This article was last reviewed on July 15, 2019 by Jason Wasserman, MD PhD FRCPC Quick facts: ​Squamous cell carcinoma is a type of cervical cancer. It is caused by a virus called human papillomavirus (HPV). Most tumours start from a pre-cancerous disease called high grade squamous intraepithelial lesion (HSIL). The normal cervix The cervix is …
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Vulva: Squamous cell carcinoma

This article was last reviewed on October 31, 2018 by Emily Goebel, MD FRCPC Quick facts: Squamous cell carcinoma is a type of vulvar cancer. It develops from the skin on the vulva. There are two different pre-cancerous diseases that can lead to squamous cell carcinoma in the vulva, high grade squamous intraepithelial neoplasia and …
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Vagina: Squamous cell carcinoma

This article was last reviewed on October 31, 2018 by Emily Goebel, MD  FRCPC Quick facts: Squamous cell carcinoma is a type of vaginal cancer. It develops from the tissue that lines the inner surface of the vagina. The female genital tract The vagina is part of the female genital tract.  It forms a canal …
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What is p16?

p16 is a protein made by normal cells throughout the body. It can also be made by abnormal cells including some types of cancers. It is a type of protein called a tumour suppressor. This means that the normal role of p16 is to stop the cell from changing into a cancer cell. After it …
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What is human papillomavirus (HPV)?

Human papillomavirus (HPV) is a sexually transmitted virus. It is very common and most sexually active adults will be exposed to the virus at some point in their lives. The virus is spread by direct contact. Human papillomavirus infects squamous cells which are normally found in the skin, mouth and throat, anal canal, and cervix. …
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