Matted lymph nodes are groups of lymph nodes that have become stuck together, forming a single mass. Lymph nodes are small, bean-shaped structures that are part of the immune system. They help the body fight infections by filtering out harmful substances. Normally, lymph nodes are separate from one another, but in certain conditions, they can …
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Ghost cells are a specific type of dead cell seen under the microscope in certain medical conditions. They are called “ghost” cells because they appear as pale, empty outlines of the original cell, almost as if the cell is a shadow or “ghost” of itself. These cells no longer function and have lost their internal …
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Anaplasia is a term pathologists use to describe cancer cells that have lost the appearance and organization of the normal cells they came from. In healthy tissue, cells are differentiated — meaning they have developed specialized shapes and functions suited to the organ they belong to. Anaplastic cells have shed this specialization entirely. They look …
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The term fibromyxoid tumour is not a final diagnosis but a descriptive term that pathologists sometimes use when looking at tissue under the microscope. It refers to tumours made up of a mix of fibrous tissue (tough, scar-like tissue) and myxoid tissue (a gelatin-like material). These tumours can be benign (noncancerous) or malignant (cancerous). They …
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Lymphoblasts are immature cells that develop into lymphocytes, a type of white blood cell that is integral to the immune system. They are part of the body’s adaptive immune response, responsible for fighting infections and providing long-term immunity. Where are lymphoblasts normally found? Lymphoblasts are primarily found in the bone marrow, the soft, spongy center …
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ECL cell hyperplasia means that the number of enterochromaffin-like (ECL) cells in the lining of the stomach has increased. ECL cells are a type of neuroendocrine cell, and they help control how much acid the stomach makes. “Hyperplasia” simply means an increase in the number of cells. ECL cell hyperplasia is a description of something …
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Intranuclear inclusions are abnormal collections of material found inside the nucleus of a cell. The nucleus is the control center of the cell where the genetic material (DNA) is stored. Under the microscope, intranuclear inclusions appear as small, round, compact areas within the nucleus that look different from the surrounding material because of their color, …
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Goblet cells are large, round, mucin-filled cells found in the body’s mucous membranes. They are responsible for producing mucus. This secretion is a protective lubricant coating the lining of various organs, including parts of your digestive and respiratory systems. Where are goblet cells normally found? Goblet cells are typically located in the linings of your …
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The term “peripheral nerve sheath tumour” (PNST) refers to a group of tumours that arise from the nerve sheath, which is the protective covering of the peripheral nerves. These nerves are the ones that extend outside the central nervous system (brain and spinal cord) to the rest of the body. The nerve sheath is made …
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In pathology, the term “blastoid” refers to cells that have features resembling immature precursor cells, known as blasts, which are typically found in the bone marrow. These cells are generally considered abnormal and can be indicative of aggressive and rapidly proliferating diseases, often seen in certain types of cancers. Microscopic features of blastoid cells Blastoid …
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