meaning

Hepatocytes

What are hepatocytes? A hepatocyte is a type of cell that is found in the liver. What do hepatocytes do? Hepatocytes are very active and versatile cells that help to keep the body healthy and balanced. They are also able to regenerate when they are damaged or lost. The functions of a hepatocyte include: Making …
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Edematous

Edematous is a term used to describe the accumulation of clear, water-like fluid inside tissue. It is also called edema. A tissue becomes edematous when a specialized type of fluid called serum leaks out of blood vessels and into the surrounding tissue. Tissue can become edematous as a result of congestive heart failure, liver disease, …
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Plasmacytoid

In pathology, cells are described as plasmacytoid if they are round and if the nucleus (the part of the cell that holds the genetic material) is located to the side of the side. Pathologists often describe the location of the nucleus as eccentric or peripheral. These cells are described as plasmacytoid because they look like …
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BRAF

BRAF is a gene that provides instructions for making the BRAF protein, a kinase enzyme that is part of the MAPK/ERK signaling pathway. In normal, healthy cells, this protein works with other proteins in the MAPK/ERK pathway to regulate cell growth and proliferation. However, a change in the BRAF gene can cause this protein to behave …
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Non-invasive

What does non-invasive mean in a pathology report? In pathology, non-invasive is used to describe a disease (typically a tumour) that remains localized and has not spread into the surrounding tissues or organs. All types of benign (noncancerous) tumours are by definition non-invasive. However, some types of early-stage malignant (cancerous) tumours are also considered non-invasive …
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Chromogranin

Chromogranin is a type of protein found primarily in neuroendocrine cells. There are three chromogranin proteins encoded by the CHGA (chromogranin A), CHGB (chromogranin B), and CHGC (chromogranin C) genes. What does chromogranin do? Chromogranins play important roles in the regulated secretion of hormones and specialized proteins called neuropeptides. They are present in small intracellular …
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Sebaceous glands

Sebaceous glands are a type of gland found in a part of the skin called the dermis.  These glands make and secrete a material called sebum which looks and feels like fat. Too much sebum can make our skin and hair feel greasy. Sebaceous glands can be found all over the body although the greatest …
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Basophils

Basophils are a type of white blood cell (WBC) that play a role in the body’s immune response. They are similar in appearance to mast cells and are known for their large, dark-staining granules in the cytoplasm (body of the cell). Basophils are relatively rare, making up between 0.5% to 1.0% of circulating white blood …
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Antral type mucosa

Antral type mucosa is the thin layer of tissue that lines the antrum, cardia, and pylorus of the stomach. The tissue is made up of different types of cells that produce and secrete various substances, including mucus and hormones which aid in digestion. What does antral type mucosa with chronic gastritis mean? Antral type mucosa …
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Fibrinopurulent exudate

Fibrinopurulent exudate is a type of fluid that accumulates at a site of tissue damage or inflammation, which contains a combination of fibrin, inflammatory cells such as neutrophils, and cellular debris. Fibrin is a protein that plays a role in blood clotting, and it can form a mesh-like network that helps to hold the exudate …
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