pathology report

PALB2 and Hereditary Breast Cancer Risk

PALB2 is a gene that helps cells repair damaged DNA. People born with a harmful change in one copy of the PALB2 gene have a higher-than-average risk of breast cancer. They also have a small increase in the risk of ovarian cancer, pancreatic cancer, and breast cancer in men. There is no widely used syndrome …
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Genetic Testing for Conditions Other Than Cancer: Understanding Your Results

Genetic testing looks for changes in a person’s DNA that can explain a health condition, predict a future one, or show how the body handles certain medicines. This article is about genetic testing for conditions other than cancer. These include inherited disorders of the heart, muscles, nerves, blood, and metabolism, as well as conditions that …
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Biphenotypic Sinonasal Sarcoma: Understanding Your Pathology Report

Biphenotypic sinonasal sarcoma (BSNS) is a rare, slow-growing cancer that starts inside the nose. It is a type of sarcoma, meaning it develops from the body’s connective tissues rather than the lining of the nose. The tumor usually grows in the upper nasal cavity or the ethmoid sinuses, the small air spaces between the eyes. …
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Leydig Cell Tumor of the Testicle: Understanding Your Pathology Report

A Leydig cell tumor is a tumor that starts from Leydig cells in the testicle. Leydig cells normally make testosterone, the main male hormone. A Leydig cell tumor belongs to a group called sex cord-stromal tumors. These tumors develop from the testicle’s supporting and hormone-producing cells rather than the cells that make sperm. Most Leydig …
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Lymphoma of the Testicle: Understanding Your Pathology Report

Lymphoma of the testicle is a cancer of immune cells called lymphocytes that is found in the testicle. When the lymphoma starts in the testicle, it is called primary testicular lymphoma. Almost all primary testicular lymphomas are diffuse large B-cell lymphoma (DLBCL). Testicular lymphoma is the most common cancer of the testicle in men over 60. …
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