pathology report

Adenocarcinoma of the Gallbladder: Understanding Your Pathology Report

Adenocarcinoma is a type of gallbladder cancer that starts in glandular cells. These cells normally produce bile and line the inner surface of the gallbladder. In adenocarcinoma, the cells grow in an abnormal and uncontrolled way, invading deeper layers of the gallbladder wall and sometimes spreading to nearby lymph nodes or organs. Symptoms Gallbladder adenocarcinoma …
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What is a loop electrosurgical excision procedure (LEEP)?

Loop electrosurgical excision procedure (LEEP) is a treatment that removes abnormal tissue from the cervix using a thin wire loop that carries an electrical current. The cervix is the lower part of the uterus that connects to the vagina. LEEP is both a treatment and a method for obtaining tissue for microscopic examination. Why is …
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Mixed Neuroendocrine Non-Neuroendocrine Neoplasm of the Appendix: Understanding Your Pathology Report

A mixed neuroendocrine non-neuroendocrine neoplasm (MiNEN) is a rare type of appendix cancer that contains two different components: A neuroendocrine carcinoma (NEC) or neuroendocrine tumor (NET), which comes from hormone-producing neuroendocrine cells. A non-neuroendocrine carcinoma, usually an adenocarcinoma (a cancer that develops from gland-forming cells). For a tumor to be called MiNEN, each component must …
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Your pathology report for poorly differentiated neuroendocrine carcinoma of the appendix

A poorly differentiated neuroendocrine carcinoma (NEC) is a rare and aggressive type of appendix cancer. It begins with neuroendocrine cells in the appendix, which normally help regulate digestion by releasing hormones in response to signals from the nervous system. Unlike well differentiated neuroendocrine tumors (NETs), which are slow-growing and often discovered by chance, poorly differentiated NECs …
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What is an excisional biopsy?

An excisional biopsy is a type of surgical procedure in which the entire abnormal area of tissue is removed so it can be examined under a microscope by a pathologist. Unlike other types of biopsies that only take a small sample, an excisional biopsy removes the whole lump, lesion, or suspicious area. This enables the …
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Your pathology report for metaplastic carcinoma of the breast

Metaplastic carcinoma is a rare and aggressive type of breast cancer. It develops when cancer cells from the breast change their appearance and begin to resemble other types of cells. For example, the tumour may contain: Squamous cells (flat cells normally found on the surface of the skin and lining surfaces of the body). Spindle-shaped …
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Hallmark Cells: Definition

Hallmark cells are a distinctive type of abnormal cell seen under the microscope in a cancer called anaplastic large cell lymphoma (ALCL). These cells are a clue that helps pathologists recognize and diagnose this disease. What do hallmark cells look like? Hallmark cells are large and have a very characteristic appearance. Their nuclei, which are …
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Atypical Lymphoid Infiltrate: Understanding Your Pathology Report

Atypical lymphoid infiltrate is a descriptive, often preliminary diagnosis. Atypical means that the cells do not look normal (hence they are not typical or usual), but they are also not clearly cancerous. Lymphoid refers to lymphocytes, a type of white blood cell that is part of the immune system. It means the biopsy shows an …
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Papillae: Definition

Papillae are small, finger-like projections of tissue that can be seen in many different parts of the body. Each papilla has a central core, usually made of connective tissue and small blood vessels, and is covered on the outside by a layer of cells. Papillae are a normal structure in certain organs, but they can …
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What is high risk HPV?

HPV, or human papillomavirus, is a very common virus that can infect the skin and mucous membranes of the body. There are more than 100 different types of HPV. Some types are considered low-risk and cause conditions like genital warts. Others are called high-risk HPV because they can cause cancer. High-risk HPV infections can affect …
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