pathology report

What is a myofibroblastic lesion/proliferation?

A myofibroblastic lesion (also called a myofibroblastic proliferation) is a descriptive term used when a tissue sample contains an increased number of myofibroblasts. Myofibroblasts are specialized cells that share features of fibroblasts (cells that make connective tissue) and muscle cells (cells that can contract). Myofibroblasts normally appear during wound healing and tissue repair, where they …
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Peripheral T Cell Lymphoma NOS: Understanding Your Pathology Report

Peripheral T cell lymphoma, not otherwise specified (PTCL-NOS), is an aggressive blood cancer that starts in mature T cells — the white blood cells that normally coordinate immune responses, help fight infections, and regulate the immune system. The word “peripheral” does not mean the cancer is located at the edges of the body; it means …
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Actinic cheilitis: Understanding Your Pathology Report

Actinic cheilitis is a precancerous condition that affects the lips, most commonly the lower lip. It develops after many years of exposure to ultraviolet (UV) radiation, usually from sunlight. The lips are covered by a thin layer of skin and mucosa that is more sensitive to sun damage than other areas of the body. Over …
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Atypical Melanocytic Proliferation: Understanding Your Pathology Report

Pathologists use the term atypical melanocytic proliferation to describe a skin growth composed of melanocytes (the cells that produce pigment) that does not appear completely normal under the microscope. The growth shows some unusual or atypical features, but not all of the features needed to confidently call it benign (noncancerous) or malignant (cancerous). It is best thought of …
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Nevus: Understanding Your Pathology Report

A nevus (plural: nevi) is the medical term for a growth or spot on the skin that develops from melanocytes, the cells that produce melanin, the pigment that gives skin and hair their color. Most nevi are harmless and are commonly called moles, although the term nevus covers a wide range of pigmented and non-pigmented …
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Psoriasiform Dermatitis: Understanding Your Pathology Report

Psoriasiform dermatitis is a term for a reactive pattern of skin changes that can result from several different underlying conditions. It is called psoriasiform because the changes resemble those seen in psoriasis. What are the symptoms of psoriasiform dermatitis? People with psoriasiform dermatitis often notice red patches of skin with a dry or flaky surface …
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Hydrosalpinx: Understanding Your Pathology Report

Hydrosalpinx is a noncancerous (benign) condition in which a fallopian tube becomes blocked at its outer end and fills with watery fluid. The fallopian tubes carry an egg from the ovary to the uterus. The name comes from two Greek words: “hydro” for water and “salpinx” for tube. The blockage is almost always at the …
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What is squamous intraepithelial lesion (SIL)?

Squamous intraepithelial lesion is an abnormal growth caused by infection with human papillomavirus (HPV). This condition affects the squamous cells, which are thin, flat cells that line certain areas of the body, including the cervix, vagina, vulva, and anus. Squamous intraepithelial lesion is considered a precancerous disease, meaning it has the potential to develop into …
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Poorly Differentiated Carcinoma: Definition

Poorly differentiated carcinoma is a carcinoma (a cancer that starts in the epithelial cells lining the surfaces of organs) whose cells look very abnormal and no longer resemble the healthy tissue they came from. The word differentiated describes how closely cancer cells still look like normal cells. When a carcinoma is poorly differentiated, the cells …
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