Invasive breast carcinoma is the most common type of breast cancer. It begins in the cells lining the ducts and lobules of the breast and then spreads through the wall of a duct or lobule into the surrounding breast tissue. The word “invasive” means the cancer cells have broken out of the duct or lobule …
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Struma ovarii is a specialized type of mature teratoma of the ovary in which thyroid tissue makes up the predominant or only component of the tumor. The word “struma” is a Latin term that has historically referred to the thyroid gland. Most cases of struma ovarii are noncancerous and behave in a completely benign way. …
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The term suspicious for malignancy is used by pathologists to describe findings that strongly suggest cancer but lack enough clear evidence to make a definitive diagnosis. When this term appears in your pathology report, it means the pathologist sees some features of cancer in your tissue sample but needs more information or additional testing before …
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DOG1 (Discovered On GIST-1) is a protein found on the surface of certain cells. Pathologists use it as a diagnostic marker, a protein they can stain for to help identify what type of tumor they are looking at. DOG1 was first discovered in gastrointestinal stromal tumors (GISTs), which is where its name comes from, but …
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Liposarcoma is a type of cancer that develops from fat cells. It is classified as a soft tissue sarcoma, which means it arises in the connective tissues of the body. Liposarcomas are most commonly found in areas where fat is normally present, such as the abdomen or limbs. While liposarcoma is rare, it is one …
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The Arias-Stella reaction is a noncancerous change most often seen in the tissue that lines the uterus, called the endometrium, and sometimes in the fallopian tube. It develops in response to pregnancy or certain hormone medications, causing the affected cells to become larger and appear unusual under the microscope. It is named after Javier Arias-Stella, …
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STAT6 (Signal Transducer and Activator of Transcription 6) is a protein found in cells. It plays a key role in transmitting signals from outside a cell to its nucleus, where genetic material is stored. This signaling helps regulate how cells grow, divide, and respond to their environment. STAT6 is especially important in controlling immune system …
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SATB2 (Special AT-rich Sequence-Binding Protein 2) is a protein that plays an important role in controlling how specific genes are turned on and off. This protein helps cells grow and function normally by organizing the genetic information inside them. SATB2 is like a “manager”, ensuring specific genes work as needed. What types of normal cells …
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This article is designed to help you understand your pathology report for CD10 positive B cell lymphoma. Each section explains an important aspect of the diagnosis and what it means for you. What is CD10 positive B cell lymphoma? CD10 positive B cell lymphoma describes a group of immune system cancers involving B cells that …
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Primary cutaneous anaplastic large cell lymphoma is a type of cancer that develops in the skin. It belongs to a group of conditions called primary cutaneous CD30-positive T-cell lymphoproliferative disorders. A lymphoma is a cancer that arises from white blood cells, and in this disease, the cancer cells come from T cells, a type of …
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