ECL cell hyperplasia refers to an increase in the number of enterochromaffin-like (ECL) cells within the stomach lining. ECL cells are neuroendocrine cells that play an important role in the regulation of acid production in the stomach. Where are ECL (enterochromaffin-like) cells normally found, and what do they do? ECL cells are normally found in …
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This article is designed to help you understand your pathology report for chronic atrophic gastritis of the stomach. Each section explains an important aspect of the diagnosis and what it means for you. What is chronic atrophic gastritis? Chronic atrophic gastritis is a medical condition where inflammation causes the lining of the stomach to become …
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Goblet cells are large, round, mucin-filled cells found in the body’s mucous membranes. They are responsible for producing mucus. This secretion is a protective lubricant coating the lining of various organs, including parts of your digestive and respiratory systems. Where are goblet cells normally found? Goblet cells are typically located in the linings of your …
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Canalicular adenoma is a benign (noncancerous) type of salivary gland tumour. It most commonly arises in a minor salivary gland, such as those in the lip and oral cavity (palate, gingiva, floor of mouth). It is a rare tumour, representing about 1% of all salivary gland tumours. What are the symptoms of a canalicular adenoma? …
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A hepatocellular (hepatic) adenoma is a rare, benign (noncancerous) liver tumour. These tumours are typically asymptomatic but can sometimes lead to complications, such as internal bleeding or even a risk of turning cancerous, especially if the adenoma is large. What are the symptoms of a hepatocellular adenoma? Although most hepatocellular adenomas do not cause symptoms, …
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Diverticular disease is a common condition in which small pouches called diverticula form in the wall of the colon. It is one of the most frequently diagnosed conditions of the large intestine in adults over fifty, and most people who have it never develop serious problems. The term covers a spectrum of conditions: Diverticulosis. Diverticula …
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Spread through air spaces, often abbreviated as STAS, is a term pathologists use to describe how lung cancer cells can invade nearby healthy lung tissue. In this pattern, cancer cells move away from the main tumour and spread into the tiny air-filled spaces within the lungs. STAS is most commonly seen in a type of …
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Lymphatic invasion describes a situation where cancer cells have moved from the primary tumor into tiny channels in the body known as lymphatic vessels. These vessels are part of the lymphatic system, a network that helps maintain fluid balance in the body and plays a crucial role in fighting infections. When cancer cells enter these …
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In pathology, rhabdoid describes tumour cells resembling immature muscle cells called rhabdomyoblasts. Although these cells resemble developing muscle cells, they are not actually muscle-related, and tumours with rhabdoid cells typically do not arise from muscle tissue. Instead, “rhabdoid” refers specifically to their appearance under a microscope. Tumours containing rhabdoid cells tend to behave aggressively and …
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Leukemia is a type of cancer that affects the blood and bone marrow, the spongy tissue inside bones where blood cells are made. It is characterized by the rapid production of abnormal white blood cells (WBCs), which are not fully developed and do not function properly. These abnormal cells can accumulate in the blood and …
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