An aneurysmal bone cyst is a benign (non-cancerous) tumour of bone composed of multiple blood-filled spaces separated by thin walls of tissue. Despite the name, it is not related to blood vessel aneurysms. The expanding cystic spaces can weaken bone and cause pain or swelling. This article explains the pathology report for aneurysmal bone cyst, …
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Grade 3 chondrosarcoma, also known as high-grade chondrosarcoma, is a type of cancer made up of cartilage that develops within the medulla (central space) of a bone. It is one of the most common types of primary bone cancer in adults. Why is the grade important? Chondrosarcomas are graded based on their appearance under the …
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Grade 2 chondrosarcoma, also known as intermediate grade chondrosarcoma, is a type of cancer made up of cartilage that develops within the medulla (central space) of a bone. It is one of the most common types of primary bone cancer in adults. Why is the grade important? Chondrosarcomas are graded based on their appearance under …
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Grade 1 chondrosarcoma, also known as low-grade chondrosarcoma, is a type of cancer made up of cartilage that develops within the medulla (central space) of a bone. It is one of the most common types of primary bone cancer in adults. Why is the grade important? Chondrosarcomas are graded based on their appearance under the …
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In pathology, the term “blastoid” refers to cells that have features resembling immature precursor cells, known as blasts, which are typically found in the bone marrow. These cells are generally considered abnormal and can be indicative of aggressive and rapidly proliferating diseases, often seen in certain types of cancers. Microscopic features of blastoid cells Blastoid …
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In pathology, the term “blasts” refers to immature cells in the early stages of development into mature cells. These cells are typically found in the bone marrow, which is part of the normal process of blood cell formation known as hematopoiesis. Blasts can develop into various types of blood cells, such as red blood cells, white …
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High-grade B cell lymphoma with MYC and BCL2 rearrangements — also called diffuse large B cell lymphoma (DLBCL) with MYC and BCL2 rearrangements, or informally “double-hit lymphoma” — is an aggressive blood cancer that starts in B cells. These white blood cells help the body fight infections. The name refers to two specific genes, MYC …
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High grade B cell lymphoma NOS (HGBL NOS) is a type of cancer that starts in the white blood cells called B cells. These cells are part of the immune system and help protect your body from infections and diseases. “High grade” means that this type of cancer is likely to grow and spread quickly …
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Cribriform morular thyroid carcinoma (CMTC) is a rare type of thyroid cancer with a distinctive appearance under the microscope and an important link to an inherited condition called familial adenomatous polyposis (FAP). The thyroid is a butterfly-shaped gland at the front of the neck that helps regulate metabolism. CMTC was once grouped with papillary thyroid …
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Calcitonin is a hormone produced by specialized cells in the thyroid gland called C cells (also known as parafollicular cells). Its primary role in the body is to help regulate blood calcium levels — when calcium levels rise too high, calcitonin lowers them by slowing bone breakdown and reducing the release of calcium into the …
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