pathology

Corpus Luteum Cyst of the Ovary: Understanding Your Pathology Report

A corpus luteum cyst is a noncancerous (benign) fluid-filled space in the ovary. It develops from the corpus luteum, a normal structure that forms in the ovary every month after an egg is released. The corpus luteum makes progesterone, the hormone that prepares the lining of the uterus for a possible pregnancy. Its name comes …
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Bile Duct Hamartoma: Understanding Your Pathology Report

What is a bile duct hamartoma? A bile duct hamartoma, also known as a von Meyenburg complex, is a non-cancerous liver tumour made up of disorganized bile ducts.  It is a common type of liver tumour seen in approximately 3-6% of the population. Some may appear before birth during the time in fetal development when …
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Schneiderian Papilloma: Understanding Your Pathology Report

A Schneiderian papilloma is a noncancerous (benign) tumor that arises from the tissue lining the nasal cavity and paranasal sinuses. Another name for it is sinonasal papilloma. Pathologists divide Schneiderian papillomas into three types, called inverted, exophytic, and oncocytic, based on how the tumor looks under the microscope. A Schneiderian papilloma is not a cancer, …
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Immunoreactivity: Definition

Immunoreactivity is a term pathologists use to describe how cells or tissues respond to a special laboratory test called immunohistochemistry (IHC). In this test, antibodies are applied to a tissue sample to look for specific proteins. If the protein being tested is present, the antibody will attach to it, and the cells will change color …
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Tangentially Sectioned: Definition

In pathology, a tangentially sectioned tissue sample is one cut at an angle rather than straight across. When a sample is cut at an angle, the layers of tissue overlap in the thin slice placed on the microscope slide. This can make the sample difficult to interpret, and sometimes it prevents the pathologist from seeing …
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Deep Fibromatosis: Understanding Your Pathology Report

Deep fibromatosis is a growth made of fibrous tissue that develops deep inside the body, in or near muscles and around internal organs. The current name for this tumor is desmoid-type fibromatosis, and your report may also call it a desmoid tumor. Older reports may use the names abdominal fibromatosis, extra-abdominal fibromatosis, or intra-abdominal fibromatosis, …
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Barrett esophagus: Understanding Your Pathology Report

Barrett esophagus is a change in the lining of the lower esophagus, the muscular tube that carries food and liquid from the mouth to the stomach. The esophagus is normally lined by squamous cells, flat, tough cells built to withstand the wear of swallowing. In Barrett esophagus, these are replaced by glandular cells of the …
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Atypical Endometrial Hyperplasia: Understanding Your Pathology Report

Atypical endometrial hyperplasia (AEH) is a precancerous condition of the lining of the uterus, which is called the endometrium. In this condition, the glands that make up the lining become crowded and irregular, and the cells lining them look abnormal. The word atypical refers to that abnormal appearance of the cells. AEH is not cancer. …
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