pathology

Bile Duct Hamartoma: Understanding Your Pathology Report

What is a bile duct hamartoma? A bile duct hamartoma, also known as a von Meyenburg complex, is a non-cancerous liver tumour made up of disorganized bile ducts.  It is a common type of liver tumour seen in approximately 3-6% of the population. Some may appear before birth during the time in fetal development when …
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Schneiderian Papilloma: Understanding Your Pathology Report

A Schneiderian papilloma is a noncancerous (benign) tumor that arises from the tissue lining the nasal cavity and paranasal sinuses. Another name for it is sinonasal papilloma. Pathologists divide Schneiderian papillomas into three types, called inverted, exophytic, and oncocytic, based on how the tumor looks under the microscope. A Schneiderian papilloma is not a cancer, …
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Immunoreactivity: Definition

Immunoreactivity is a term pathologists use to describe how cells or tissues respond to a special laboratory test called immunohistochemistry (IHC). In this test, antibodies are applied to a tissue sample to look for specific proteins. If the protein being tested is present, the antibody will attach to it, and the cells will change color …
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Tangentially Sectioned: Definition

In pathology, a tangentially sectioned tissue sample is one cut at an angle rather than straight across. When a sample is cut at an angle, the layers of tissue overlap in the thin slice placed on the microscope slide. This can make the sample difficult to interpret, and sometimes it prevents the pathologist from seeing …
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Deep Fibromatosis: Understanding Your Pathology Report

Background: Deep fibromatosis or desmoid tumour is a benign (non-cancerous) type of tumour that starts in connective tissue. It is considered locally aggressive because it can grow into surrounding tissues and organs. The tumour can also grow back if not completely removed. However, it will not metastasize (spread) to other body parts. Other names for …
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Barrett esophagus: Understanding Your Pathology Report

Barrett esophagus is a change in the lining of the lower esophagus, the muscular tube that carries food and liquid from the mouth to the stomach. The esophagus is normally lined by squamous cells, flat, tough cells built to withstand the wear of swallowing. In Barrett esophagus, these are replaced by glandular cells of the …
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Atypical Endometrial Hyperplasia: Understanding Your Pathology Report

Atypical endometrial hyperplasia (AEH) is a precancerous condition of the lining of the uterus, called the endometrium. In AEH, the endometrium becomes abnormally thick and the glandular cells that make up the endometrium start to grow in a crowded and irregular pattern. The cells also look abnormal under the microscope, which is why the word …
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