What does inactive endometrium mean? Inactive endometrium is a term pathologists use to describe the appearance of endometrial tissue (the tissue found on the inside of the uterus) that is not under the influence of normal (physiological) levels of estrogen and progesterone or is altered due to exogenous factors. Is inactive endometrium normal? Inactive endometrium …
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In a pathology report, the term non-invasive means that a tumour or abnormal growth has not spread into the surrounding tissues. The abnormal cells are confined to the original layer of tissue where they started. This term is most often used to describe early-stage cancers or pre-cancerous conditions, but it also applies to all benign …
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Squamous cell carcinoma in situ is a non-invasive type of cancer made up of squamous cells. It is called non-invasive because the abnormal cells have not spread into any of the surrounding tissues. If left untreated, this condition can turn into a type of invasive cancer called squamous cell carcinoma. Squamous cell carcinoma in situ …
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PAX5 is a protein that acts as a transcription factor, which means it helps control when certain genes are turned on or off in a cell. It plays an important role in the early development of the immune system by guiding immature blood cells to become B cells, a type of white blood cell that …
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What is extranodal marginal zone lymphoma of mucosal-associated lymphoid tissue? Extranodal marginal zone lymphoma (EMZL) of mucosal-associated lymphoid tissue (MALT) is a type of cancer made up of immune cells called B cells. It is considered an indolent type of cancer because the tumour grows very slowly and the cells are unlikely to spread to …
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What does gastric dysplasia mean? Gastric dysplasia is a precancerous change that can turn into a type of stomach cancer called adenocarcinoma over time. Another name for this condition is glandular intraepithelial neoplasia. Where in the stomach does dysplasia start? Gastric dysplasia in the stomach starts from specialized epithelial cells that cover the inside surface …
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Chromogranin is a family of proteins primarily found in neuroendocrine cells—specialized cells that release hormones into the blood in response to signals from the nervous system. The main types are chromogranin A, B, and C. These proteins play a crucial role in the storage and release of hormones. Why do pathologists test for chromogranin? Pathologists …
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Sebaceous glands are a type of gland found in the dermis of the skin. These glands make and secrete sebum, which looks and feels like fat. Too much sebum can make our skin and hair feel greasy. Sebaceous glands can be found all over the body, although most are found on the face and scalp. …
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Background: Atypical lobular hyperplasia (ALH) of the breast is a benign (non-cancerous) condition characterized by an abnormal increase in the number of epithelial cells in the lobules of the breast. This condition involves cells that look different from normal cells but are not abnormal enough to be classified as cancer. Atypical lobular hyperplasia is considered …
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What is a ganglioneuroma? Ganglioneuroma is a rare type of non-cancerous tumour made up of cells normally found in the nervous system including ganglion cells, nerve fibers, and Schwann cells. What causes ganglioneuroma? Most people who develop a ganglioneuroma have no known risk factors and the cause remains unknown. People with the genetic syndrome multiple …
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