Glandular cells are specialized epithelial cells that form the functional units of most internal organs. They are involved in the production and secretion of substances that aid in the normal activity of the organ. These substances may include enzymes, hormones, mucus, or other products that are released into ducts, surfaces, or the bloodstream for various …
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Endosalpingiosis is a condition in which tissue that normally lines the inside of the fallopian tube is found somewhere else in the body. It is most often found in the pelvis, including on the surface of the ovaries, on the peritoneum (the lining of the abdominal cavity), and in nearby lymph nodes. Endosalpingiosis is a …
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Metastatic carcinoma refers to cancer that has spread from its original (primary) site to other parts of the body. The term carcinoma specifically refers to a type of cancer that begins in the epithelial cells, which line the organs and tissues of the body. For example, if someone has metastatic carcinoma of the breast, it …
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A fibrovascular core is a small microscopic structure made up of fibrous tissue (connective tissue) and blood vessels. These cores are found inside finger-like projections called papillae. Papillae are common features in many types of growths, including both benign (noncancerous) and malignant (cancerous) ones. For example, fibrovascular cores can be seen in benign papillomas, as …
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Psammoma bodies are tiny, rounded structures often found within certain types of tumours. Under a microscope, they appear as small, layered (concentric) deposits made up of calcium and proteins, resembling the layers of an onion. The name “psammoma” comes from the Greek word “psammos”, meaning “sand,” because of their sand-like appearance under the microscope, and …
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A vascular lesion is an abnormal growth made mostly of blood vessels or the cells that line them. Doctors call these cells endothelial cells. The term covers many different conditions. Some are normal healing responses, some are present from birth, some are noncancerous tumors, and a few are cancers. Vascular lesions can occur anywhere in …
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Melan-A (also known as Mart-1) is a protein made by certain types of cells in the body. It is most commonly found in melanocytes, which produce melanin, a pigment that gives colour to skin, hair, and eyes. Melan-A is also important in pathology because it can help pathologists identify specific types of tumours. What is …
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A well differentiated neuroendocrine tumor is a cancer made of neuroendocrine cells that still look much like normal neuroendocrine cells. Doctors often abbreviate it as NET. These tumors can start in many organs, including the pancreas, the digestive tract, and the lungs. Many grow slowly, but some grow faster, and some spread to other parts …
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A poorly differentiated neuroendocrine carcinoma is a type of cancer made up of specialized cells called neuroendocrine cells. Neuroendocrine cells normally produce hormones and are found throughout the body, including the lungs, digestive tract, and many other organs. The term “poorly differentiated” means the cancer cells look very abnormal compared to healthy neuroendocrine cells. Because …
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Neuroendocrine carcinoma (NEC) is a type of cancer composed of cells that exhibit features of both nerve cells and hormone-producing cells, also known as neuroendocrine cells. These cancers are considered high-grade tumours, which means they tend to grow quickly and may spread to other parts of the body. Neuroendocrine carcinomas can start in many different …
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