Chromogranin is a type of protein found primarily in neuroendocrine cells. There are three chromogranin proteins encoded by the CHGA (chromogranin A), CHGB (chromogranin B), and CHGC (chromogranin C) genes. What does chromogranin do? Chromogranins play important roles in the regulated secretion of hormones and specialized proteins called neuropeptides. They are present in small intracellular …
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What is a well differentiated neuroendocrine tumour? A well differentiated neuroendocrine tumour (NET) is a type of cancer made up of specialized neuroendocrine cells. The tumour is described as “well differentiated” because the cells in the tumour look very similar to normal, healthy neuroendocrine cells. These tumours can be found almost anywhere in the body. …
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What is a neuroendocrine carcinoma? Neuroendocrine carcinoma (NEC) is a type of cancer made up of specialized neuroendocrine cells. Neuroendocrine carcinoma can be found almost anywhere in the body. Other names for this type of cancer are poorly differentiated neuroendocrine carcinoma and poorly differentiated neuroendocrine neoplasm (NEN). What are neuroendocrine cells? Neuroendocrine cells are a …
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What is a neuroendocrine tumour? A neuroendocrine tumour (NET) is a type of cancer made up of specialized neuroendocrine cells. Neuroendocrine tumours can be found almost anywhere in the body. Another name for this type of cancer is neuroendocrine neoplasm (NEN). What are neuroendocrine cells? Neuroendocrine cells are a specialized type of cell that are …
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What is a well differentiated neuroendocrine tumour in the appendix? Well differentiated neuroendocrine tumour (NET) is a cancer and the most common type of cancer in the appendix. The tumour is made up of specialized neuroendocrine cells that are normally found inside the appendix. Pathologists divide well differentiated NETs of the appendix into three grades …
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What are neuroendocrine cells? Neuroendocrine cells are specialized cells that function as part of both the nervous and endocrine systems of the body. Neuroendocrine cells are found throughout the body. Normal neuroendocrine cells are often hard to see under the microscope because they are small and hidden between other types of cells. When examined on …
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A pheochromocytoma is a type of neuroendocrine tumour that originates from the chromaffin cells of the adrenal gland, which is located on top of the kidneys. These cells are responsible for producing and releasing hormones like adrenaline and noradrenaline, which are crucial for your body’s stress response. Most (about 75-90%) of pheochromocytomas are non-cancerous tumours. …
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What is Merkel cell carcinoma? Merkel cell carcinoma is a type of skin cancer. It develops from the Merkel cells normally found in the skin. Merkel cells are neuroendocrine cells and Merkel cell carcinoma is a type of neuroendocrine tumour. For this reason, another name for Merkel cell carcinoma is primary neuroendocrine carcinoma of the …
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Carcinoid is a type of cancer made up of neuroendocrine cells. Most start in the lungs where they are divided into two groups – typical carcinoid and atypical carcinoid. These tumours can also be found in the colon and pancreas where they are usually given the name well differentiated neuroendocrine tumour. Is a carcinoid a …
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