pathology report

Lentigo Maligna Melanoma: Understanding Your Pathology Report

Lentigo maligna melanoma is a type of melanoma, a skin cancer that develops from melanocytes, the pigment-producing cells of the skin. It arises in skin with heavy long-term sun damage, such as the face, neck, and arms, and it usually affects older adults with lighter skin. It begins as a noninvasive cancer called lentigo maligna, …
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Striated Duct Adenoma: Understanding Your Pathology Report

Striated duct adenoma is a rare, benign tumour that develops in the salivary glands, most often in the parotid gland, situated in front of and below the ears. The tumour is made up of small ducts (tiny tube-like structures) similar to those normally found in the salivary glands. These tumours are typically slow-growing and do …
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What is a smooth muscle neoplasm?

Smooth muscle neoplasm is a descriptive term used by pathologists to describe a tumour composed of smooth muscle cells. Smooth muscle is the type of muscle found in organs that move automatically, such as the walls of blood vessels, the digestive tract, and the uterus. Under the microscope, smooth muscle cells appear long and thin, …
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IgG4 Related Disease: Definition

IgG4-related disease is a rare autoimmune condition where the immune system becomes overactive and mistakenly attacks healthy tissues in the body. It can affect many organs, including the pancreas, salivary glands, bile ducts, kidneys, and lymph nodes. This disease is called “IgG4-related” because it is associated with increased levels of a specific antibody called IgG4. …
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What is a myofibroblastic lesion/proliferation?

A myofibroblastic lesion (also called a myofibroblastic proliferation) is a descriptive term used when a tissue sample contains an increased number of myofibroblasts. Myofibroblasts are specialized cells that share features of fibroblasts (cells that make connective tissue) and muscle cells (cells that can contract). Myofibroblasts normally appear during wound healing and tissue repair, where they …
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Peripheral T Cell Lymphoma NOS: Understanding Your Pathology Report

Peripheral T cell lymphoma, not otherwise specified (PTCL-NOS), is an aggressive blood cancer that starts in mature T cells — the white blood cells that normally coordinate immune responses, help fight infections, and regulate the immune system. The word “peripheral” does not mean the cancer is located at the edges of the body; it means …
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