GATA3 (GATA binding protein 3) is a protein found in the nucleus of specific cells. It plays a crucial role in regulating how these cells grow and develop by controlling the activity of specific genes. GATA3 is especially important in the normal development of breast tissue, the urinary tract (urothelium), and certain immune cells. What …
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An abscess is a localized collection of pus — a thick fluid made up of dead cells, debris, and immune cells — that builds up inside body tissue. It forms when the body’s immune system mounts a strong response to an injury, infection, or other source of irritation, and the responding cells accumulate faster than …
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Parakeratosis is a word pathologists use to describe a change in the surface layer of squamous epithelium, which is the tissue that lines many parts of the body including the skin, mouth, throat, esophagus, cervix, and anal canal. In healthy tissue, the squamous cells at the surface mature and lose their nuclei (the part of …
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Lynch syndrome is an inherited condition that significantly increases the risk of developing several types of cancer, most commonly colorectal (colon and rectal) cancer and endometrial (uterine) cancer. It is caused by an inherited change in one of the genes responsible for making mismatch repair (MMR) proteins — a group of proteins that normally find …
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Hypertrophy is a non-cancerous condition characterized by an increase in the size of individual cells, resulting in an overall enlargement of the affected tissue or organ. It differs from hyperplasia, which involves increasing the number of cells rather than their size. The term hypertrophic is also used to describe tissues that have undergone hypertrophy. What …
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What is a granular cell tumour? Granular cell tumour is a non-cancerous type of tumour made up of large pink granular cells. The tumour is believed to originate from cells normally found in neural tissue such as a nerve. Granular cell tumours can develop anywhere in the body although they are most commonly found inside …
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What is chronic rhinosinusitis? Chronic rhinosinusitis is a medical condition caused by inflammation of the nasal cavity and paranasal sinuses. It is a very common condition that typically affects adults. People with chronic rhinosinusitis are more likely to develop non-cancerous growth in the nasal cavity or paranasal sinuses called a sinonasal inflammatory polyp. What causes …
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What is a sinonasal inflammatory polyp? A sinonasal inflammatory polyp is a non-cancerous growth that may develop in the nasal cavity or paranasal sinuses. It is a very common condition that affects up to 20% of the adult population in some parts of the world. What causes a sinonasal inflammatory polyp? Sinonasal inflammatory polyps can …
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Help support MyPathologyReport As a not-for-profit charity (registered charity 769563271RR0001), we rely on donations to help support our work. By donating MyPathologyReport today, you will help ensure that patients have access to the resources they need to read and understand their pathology reports. Where does my donation go? All of the money we receive is …
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What is uterine leiomyosarcoma? Uterine leiomyosarcoma is a type of uterine cancer. The tumour starts from specialized smooth muscle cells normally found in a part of the uterus called the myometrium. Most patients are over the age of 50 years at the time of diagnosis. What are the symptoms of uterine leiomyosarcoma? Symptoms of uterine leiomyosarcoma …
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