Synaptophysin is a protein found in certain types of cells, particularly those in the nervous system and in neuroendocrine cells, which are specialized cells that release hormones in response to nerve signals. Synaptophysin is located on small storage sacs called synaptic vesicles, which are used to send messages between nerve cells or to release hormones. Because …
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Urothelial carcinoma in situ (CIS) is a type of non-invasive cancer that starts in the lining of the urinary tract. The urinary tract includes the bladder, kidneys, ureters, and urethra. “In situ” means that the cancer cells are only found in the urothelium (inner lining) and have not spread to deeper tissues. However, if not …
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A mitotically active cellular fibroma is a noncancerous (benign) tumor of the ovary. It grows from fibroblasts, the cells that make the firm supporting tissue found inside the ovary. It belongs to a family of tumors called sex cord-stromal tumors. The long name describes two things the pathologist saw. “Cellular” means the tumor cells are …
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A cellular fibroma is a noncancerous (benign) tumor of the ovary. It grows from fibroblasts, the cells that make the firm supporting tissue found inside the ovary. It belongs to a family of tumors called sex cord-stromal tumors. The word “cellular” describes what the pathologist sees under the microscope. In an ordinary ovarian fibroma, the …
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An ovarian fibroma is a noncancerous (benign) tumor of the ovary. It grows from fibroblasts, the cells that make the firm supporting tissue found inside the ovary. Because it is made almost entirely of this supporting tissue, an ovarian fibroma is solid and firm rather than fluid-filled. It belongs to a family of tumors called …
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What does mucinous mean? Mucinous is used in pathology reports to describe the presence of a material called mucin inside cells (intracellular mucin) or in the tissue surrounding the cells (extracellular mucin). Mucin is a protein that is used to make a thick fluid called mucus. Mucin is made by many normal cells throughout the …
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An inflammatory polyp is a non-cancerous growth on the inner lining of the colon or rectum. It forms in response to injury or inflammation. It is not cancer, it is not precancerous, and finding one does not mean cancer is present. These polyps develop when the colon lining is damaged repeatedly, and the tissue grows …
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In pathology, the word intracytoplasmic refers to anything found inside the cytoplasm of a cell. The cytoplasm is the jelly-like material inside each cell that surrounds the nucleus. It contains many small structures called organelles, which help the cell function, store energy, and remove waste. When pathologists examine cells under a microscope, they often describe …
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Eosinophils are a type of white blood cell (WBC) and a part of the body’s innate immune system. They help protect the body against allergens and infections. When examined under the microscope, eosinophils are small cells with bright pink cytoplasm. The cytoplasm of the cell is filled with small round granules and the nucleus has …
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Neutrophils are a type of white blood cell and an important part of the body’s innate immune system, which is the body’s first line of defense against infection and injury. They are the most common type of white blood cell, making up between 50% and 80% of all white blood cells in the bloodstream. Neutrophils …
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