High grade dysplasia is a precancerous condition made up of cells that look very abnormal under the microscope. These abnormal cells differ significantly from healthy cells in both their size and shape, and they are often arranged in a disorganized manner within the tissue. Although these cells are not yet cancerous, they have a high …
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In pathology, the term low grade describes cells that look abnormal under the microscope but still share some features with normal, healthy cells. To determine if cells are low grade, pathologists compare them to the normal cells typically found in the same part of the body. Low grade is different from high grade, which describes cells that …
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In pathology, cytologic atypia describes cells that look abnormal when examined under a microscope. Cells may show cytologic atypia because of their shape, size, or colour. These changes can affect the cytoplasm (body) of the cell or the nucleus (the part of the cell that holds the genetic material). Does cytologic atypia mean the cells …
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What is a traditional serrated adenoma? Traditional serrated adenoma (TSA) is a precancerous growth and a type of polyp found in the colon and rectum. Is traditional serrated adenoma cancer? No. TSA is not cancer. However, it is considered a precancerous growth because over time it can turn into a type of colon cancer called …
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What is endometrioid intraepithelial neoplasia? Endometrioid intraepithelial neoplasia (EIN) is a precancerous condition associated with an abnormally thick endometrium. It is considered a precancerous condition because over time it can turn into a type of endometrial cancer called endometrioid adenocarcinoma. Another name for this condition is atypical endometrial hyperplasia. Is endometrioid intraepithelial neoplasia cancer? No. …
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Endometrial clear cell carcinoma is a rare but aggressive type of cancer that starts in the lining of the uterus, called the endometrium. The cancer cells in this type of tumour often look clear under the microscope, which is why it is called “clear cell carcinoma.” Endometrial clear cell carcinoma is considered a high grade …
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A benign phyllodes tumor is a rare, non-cancerous breast tumor that arises from the stroma (supportive connective tissue) within the breast. Unlike malignant or borderline types, benign phyllodes tumors grow slowly. They do not spread beyond their original location or to other parts of the body. What causes benign phyllodes tumors? The exact cause of …
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Background: Fibrous histiocytoma is a common benign (non-cancerous) skin tumour. It is made up of a combination of fibroblastic cells, macrophages, and collagen, a type of connective tissue. The tumour develops in a layer of skin called the dermis. Another name for a fibrous histiocytoma is dermatofibroma. What are the symptoms of a fibrous …
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High grade prostatic intraepithelial neoplasia (HGPIN) is a condition in which the cells that line the ducts and glands of the prostate gland show abnormal changes. These changes are not cancerous, but they are considered precancerous, meaning they may develop into prostate cancer over time. HGPIN is often detected in prostate biopsies, which are usually …
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In this section, our team of pathologists answers some of the most common questions about pathology and pathology reports. If you have additional questions, feel free to contact us. What is a pathology report? A pathology report is a medical document that explains what was found when a pathologist examined a tissue sample. It describes …
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