Struma ovarii is a specialized type of mature teratoma of the ovary in which thyroid tissue makes up the predominant or only component of the tumor. The word “struma” is a Latin term that has historically referred to the thyroid gland. Most cases of struma ovarii are noncancerous and behave in a completely benign way. …
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The term suspicious for malignancy is used by pathologists to describe findings that strongly suggest cancer but lack enough clear evidence to make a definitive diagnosis. When this term appears in your pathology report, it means the pathologist sees some features of cancer in your tissue sample but needs more information or additional testing before …
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DOG1 (Discovered on GIST-1) is a protein found on the surface of certain cells. It is commonly used in pathology to identify specific types of tumours. DOG1 was first identified in gastrointestinal stromal tumours (GISTs), but it can also be found in other normal tissues and tumours. What is the function of DOG1? Although DOG1’s …
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Liposarcoma is a type of cancer that develops from fat cells. It is classified as a soft tissue sarcoma, which means it arises in the connective tissues of the body. Liposarcomas are most commonly found in areas where fat is normally present, such as the abdomen or limbs. While liposarcoma is rare, it is one …
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The Arias-Stella reaction is a noncancerous change typically seen in the tissue lining the uterus (the endometrium) or the fallopian tube. It occurs in response to pregnancy or certain hormone medications. The cells become larger and sometimes appear unusual when examined under a microscope. The reaction is named after the pathologist who first described it. …
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STAT6 (Signal Transducer and Activator of Transcription 6) is a protein found in cells. It plays a key role in transmitting signals from outside a cell to its nucleus, where genetic material is stored. This signaling helps regulate how cells grow, divide, and respond to their environment. STAT6 is especially important in controlling immune system …
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SATB2 (Special AT-rich Sequence-Binding Protein 2) is a protein that plays an important role in controlling how specific genes are turned on and off. This protein helps cells grow and function normally by organizing the genetic information inside them. SATB2 is like a “manager”, ensuring specific genes work as needed. What types of normal cells …
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This article is designed to help you understand your pathology report for CD10 positive B cell lymphoma. Each section explains an important aspect of the diagnosis and what it means for you. What is CD10 positive B cell lymphoma? CD10 positive B cell lymphoma describes a group of immune system cancers involving B cells that …
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This article is designed to help you understand your pathology report for primary cutaneous anaplastic large cell lymphoma. Each section explains an important aspect of the diagnosis and what it means for you. What is primary cutaneous anaplastic large cell lymphoma? Primary cutaneous anaplastic large cell lymphoma is a type of cancer that develops in …
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Angioimmunoblastic T-cell lymphoma (AITL) is a rare and aggressive form of lymphoma that affects the immune system. It develops from T cells, a type of white blood cell that normally helps regulate the immune response. This type of lymphoma typically begins in the lymph nodes but can also affect other parts of the body, including …
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