pathology report

Paratubal Cyst: Understanding Your Pathology Report

What is a paratubal cyst? A paratubal cyst is a noncancerous fluid-filled space that develops between the ovary and the fallopian tube. It is a common condition that more often affects children and young women. What are the symptoms of a paratubal cyst? Most paratubal cysts do not cause any symptoms and the cyst is …
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Cyclin D1: Definition

Cyclin D1 is part of a family of proteins called cyclins. All cyclins are cell cycle regulators, meaning they help determine when a cell can divide (to create two new cells). Cyclins can be further broken down into multiple families and subtypes. These all work in slightly different ways, but they all push cells to …
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What is smooth muscle actin (SMA)?

SMA stands for smooth muscle actin, a type of protein found inside certain cells in the body. It plays an important role in helping cells move and maintain their shape. There are different types of actin proteins, but alpha smooth muscle actin (α-SMA) is the type most commonly used in pathology testing. Pathologists use SMA …
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Angioleiomyoma: Understanding Your Pathology Report

Angioleiomyoma is a benign (noncancerous) soft tissue tumour that develops from smooth muscle cells, the same cells found in the walls of blood vessels. These tumours usually arise in the dermis (the deep layer of the skin) or subcutis (the fat just beneath the skin). Under the microscope, the tumour cells grow in bundles surrounding …
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Classic Follicular Lymphoma: Understanding Your Pathology Report

Classic follicular lymphoma is a type of blood cancer that starts in B cells — specialized white blood cells that normally help the body fight infection. It is the second most common lymphoma in adults and is considered an indolent, or slow-growing, cancer. Most people are diagnosed when they notice a painless lump or swelling, …
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Plasmablastic Lymphoma: Understanding Your Pathology Report

What is plasmablastic lymphoma? Plasmablastic lymphoma (PBL) is a rare and aggressive type of immune system cancer and a type of non-Hodgkin lymphoma (NHL). The tumour is made up of plasma cells that arose from B cells. What are the symptoms of plasmablastic lymphoma? The symptoms of PBL depend on where in the body the …
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Aggressive B Cell Lymphoma: Understanding Your Pathology Report

Aggressive B cell lymphoma is a term used to describe a group of immune system cancers made up of cells called B cells. Although this is considered enough to establish a formal diagnosis, additional tests might be needed to refine how best to group or subclassify the disease. What types of B cell lymphoma are …
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Your pathology report for inflammatory myofibroblastic tumour (IMT)

What is an inflammatory myofibroblastic tumour? Inflammatory myofibroblastic tumour (IMT) is a rare type of tumour that typically behaves in a noncancerous manner. It can be found anywhere in the body including the abdomen, pelvis, urinary tract, digestive tract, female reproductive organs, head and neck, and lungs. Is inflammatory myofibroblastic tumour benign or malignant? Although …
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Pseudosarcomatous Myofibroblastic Proliferation: Understanding Your Pathology Report

A pseudosarcomatous myofibroblastic proliferation is a non-cancerous growth that can develop after certain surgical procedures or manipulations. Although it may sometimes be mistaken for cancer under a microscope, this condition is entirely benign (non-cancerous). Other names for this condition include postoperative spindle cell nodule and pseudosarcomatous myofibroblastic neoplasm. Where are pseudosarcomatous myofibroblastic proliferations typically found? Pseudosarcomatous …
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Postoperative Spindle Cell Nodule: Understanding Your Pathology Report

A postoperative spindle cell nodule is a non-cancerous growth that can develop after certain surgical procedures or manipulations. Although it may sometimes be mistaken for cancer under a microscope, this condition is entirely benign (non-cancerous). Other names for this condition include pseudosarcomatous myofibroblastic proliferation and pseudosarcomatous myofibroblastic neoplasm. Where are postoperative spindle cell nodules typically …
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