pathology report

What is neuroendocrine carcinoma?

Neuroendocrine carcinoma (NEC) is a type of cancer composed of cells that exhibit features of both nerve cells and hormone-producing cells, also known as neuroendocrine cells. These cancers are considered high-grade tumours, which means they tend to grow quickly and may spread to other parts of the body. Neuroendocrine carcinomas can start in many different …
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What is a neuroendocrine tumor?

A neuroendocrine tumor (NET) is a type of cancer that starts from neuroendocrine cells. These are specialized cells with features of both nerve cells and hormone-producing cells that help regulate important body functions by releasing hormones in response to signals from the nervous system. Neuroendocrine cells are found throughout the body, which means neuroendocrine tumors …
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What is nuclear atypia?

In a pathology report, the term nuclear atypia is used to describe cells that have abnormal-looking nuclei when examined under a microscope. The nucleus is the part of the cell that contains its genetic material (DNA) and controls how the cell functions. Pathologists use the word “atypia” to mean that something looks unusual or different …
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Low Grade Dysplasia: Definition

Low grade dysplasia is a precancerous condition characterized by mildly abnormal cells that grow differently from normal, healthy cells. When examined under a microscope, these abnormal cells still closely resemble normal cells, which is why the condition is termed “low grade.” This is in contrast to high grade dysplasia, where the cells appear more abnormal …
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What is high grade dysplasia?

High grade dysplasia is a precancerous condition made up of cells that look very abnormal under the microscope. These abnormal cells differ significantly from healthy cells in both their size and shape, and they are often arranged in a disorganized manner within the tissue. Although these cells are not yet cancerous, they have a high …
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Low Grade: Definition

In pathology, the term low grade describes cells that look abnormal under the microscope but still share some features with normal, healthy cells. To determine if cells are low grade, pathologists compare them to the normal cells typically found in the same part of the body. Low grade is different from high grade, which describes cells that …
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Traditional Serrated Adenoma: Understanding Your Pathology Report

A traditional serrated adenoma is a type of polyp that develops on the inner lining of the colon or rectum. Although these polyps are not cancer, they are considered precancerous, which means they can turn into cancer over time if not removed. Most traditional serrated adenomas are found during a routine colonoscopy and are removed …
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Endometrial Clear Cell Carcinoma: Understanding Your Pathology Report

Endometrial clear cell carcinoma is a rare type of cancer that starts in the endometrium, the inner lining of the uterus. It is considered a high-grade tumour, meaning it has a higher chance of spreading beyond the uterus compared to low-grade endometrial cancers. Endometrial clear cell carcinoma behaves differently from the more common endometrial endometrioid …
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Benign Phyllodes Tumor: Understanding Your Pathology Report

A benign phyllodes tumor is a rare, non-cancerous breast tumor that arises from the stroma (supportive connective tissue) within the breast. Unlike borderline or malignant types, benign phyllodes tumors grow slowly. They do not spread beyond their original location or to other parts of the body. What causes a benign phyllodes tumors? The exact cause …
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