pathology report

What is hypercellular?

What does hypercellular mean? Hypercellular is a term pathologists use to describe an increased number of cells compared to normal in an area of the body. It is a descriptive term and not a diagnosis. Hypercellular can be used to describe both benign (non-cancerous) groups of cells and malignant (cancerous) tumours. Pathologists commonly use the …
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What is an atypical mitosis?

Atypical mitosis refers to abnormal cell division. Normally, cells divide evenly through a process called mitosis, where each new cell receives an equal amount of genetic material (DNA). However, sometimes errors occur during this process, causing the new cells to receive an uneven or abnormal amount of DNA. Pathologists describe these abnormal divisions as “atypical …
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What is an atypical mitotic figure?

An atypical mitotic figure is an abnormal pattern of cell division seen when cells split into two new cells. Normally, cells divide evenly through a process called mitosis, ensuring each new cell receives an equal amount of genetic material (DNA). However, sometimes mistakes occur, causing the cells to divide incorrectly and resulting in uneven or …
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What is non-necrotizing granulomatous inflammation?

Non-necrotizing granulomatous inflammation is a term used by pathologists to describe a specific type of long-lasting or chronic inflammation seen in the body. It occurs when your immune system forms small, round structures called granulomas to isolate and remove something it sees as harmful. Granulomas act like barriers, helping to surround and contain the harmful …
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What is necrotizing granulomatous inflammation?

Necrotizing granulomatous inflammation is a specific pattern of long-standing or chronic inflammation seen under the microscope. It occurs when the immune system attempts to isolate and eliminate a harmful substance, such as an infection, foreign material, or a component of an autoimmune response. The word “necrotizing” refers to the presence of dead tissue in the …
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Vasculitis: Definition

Vasculitis is a condition involving inflammation of the blood vessels. These include arteries, veins, and small capillaries, which carry blood to and from your organs and tissues. When these vessels become inflamed, they can become damaged and may not function properly, affecting blood flow throughout the body. Vasculitis can range from mild to severe, depending …
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H. Pylori: Definition

What does H. pylori mean in a pathology report? H. pylori stands for Helicobacter pylori and it is a type of bacteria that infects the stomach. It is a common bacteria that may be found throughout the world. Most people who are infected with Helicobacter will not experience any symptoms. However, in some people, the …
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What is helicobacter pylori?

Helicobacter pylori (H. pylori) is a type of bacteria that infects the stomach. It is one of the most common bacterial infections worldwide, usually acquired during childhood. H. pylori is unique because it can survive in the stomach’s acidic environment. It produces an enzyme called urease, which neutralizes stomach acid, allowing the bacteria to colonize …
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Epstein-Barr Virus-Encoded Small RNAs (EBER): Definition

EBER stands for Epstein-Barr virus-encoded small RNAs. These are small, non-coding RNAs produced by the Epstein-Barr virus (EBV), a member of the herpesvirus family. EBERs are among the most abundant viral RNAs present in EBV-infected cells. There are two main types, EBER1 and EBER2. Despite their high abundance in EBV-infected cells, the exact functions of …
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Epstein-Barr Virus (EBV): Definition

Epstein-Barr virus (EBV) is a member of a large group of viruses called herpesviruses. Another name for EBV is human herpesvirus 4 (HHV4). EBV is found all over the world and infection is common. How is Epstein-Barr virus spread? EBV is spread between people through body fluids, typically saliva. What are the symptoms of Epstein-Barr …
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