Histiocytes are a type of immune cell that are part of the body’s defense mechanism against infections and foreign substances. They belong to the mononuclear phagocyte system including monocytes in the blood and macrophages in tissues. Histiocytes play an important role in the immune system’s response to pathogens and tissue repair and maintenance. They are …
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In pathology, hypocellular describes tissue or organs that contain fewer cells than expected. A decrease in the number of cells can occur naturally with age or result from certain medical conditions, treatments, or injuries. Hypocellularity can affect different types of tissues, but is most commonly discussed in relation to tumours or bone marrow. What causes hypocellular tissue? …
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What does hypercellular mean? Hypercellular is a term pathologists use to describe an increased number of cells compared to normal in an area of the body. It is a descriptive term and not a diagnosis. Hypercellular can be used to describe both benign (non-cancerous) groups of cells and malignant (cancerous) tumours. Pathologists commonly use the …
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Atypical mitosis refers to abnormal cell division. Normally, cells divide evenly through a process called mitosis, where each new cell receives an equal amount of genetic material (DNA). However, sometimes errors occur during this process, causing the new cells to receive an uneven or abnormal amount of DNA. Pathologists describe these abnormal divisions as “atypical …
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An atypical mitotic figure is an abnormal pattern of cell division seen when cells split into two new cells. Normally, cells divide evenly through a process called mitosis, ensuring each new cell receives an equal amount of genetic material (DNA). However, sometimes mistakes occur, causing the cells to divide incorrectly and resulting in uneven or …
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Non-necrotizing granulomatous inflammation is a term used by pathologists to describe a specific type of long-lasting or chronic inflammation seen in the body. It occurs when your immune system forms small, round structures called granulomas to isolate and remove something it sees as harmful. Granulomas act like barriers, helping to surround and contain the harmful …
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Necrotizing granulomatous inflammation is a specific pattern of long-standing or chronic inflammation seen under the microscope. It occurs when the immune system attempts to isolate and eliminate a harmful substance, such as an infection, foreign material, or a component of an autoimmune response. The word “necrotizing” refers to the presence of dead tissue in the …
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Vasculitis is a condition involving inflammation of the blood vessels. These include arteries, veins, and small capillaries, which carry blood to and from your organs and tissues. When these vessels become inflamed, they can become damaged and may not function properly, affecting blood flow throughout the body. Vasculitis can range from mild to severe, depending …
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What does H. pylori mean in a pathology report? H. pylori stands for Helicobacter pylori and it is a type of bacteria that infects the stomach. It is a common bacteria that may be found throughout the world. Most people who are infected with Helicobacter will not experience any symptoms. However, in some people, the …
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Helicobacter pylori (H. pylori) is a type of bacteria that infects the stomach. It is one of the most common bacterial infections worldwide, usually acquired during childhood. H. pylori is unique because it can survive in the stomach’s acidic environment. It produces an enzyme called urease, which neutralizes stomach acid, allowing the bacteria to colonize …
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