pathology report

What is CD68?

CD68 is a protein normally found on the surface of macrophages, a type of immune cell, and cells related to macrophages. Macrophages help protect your body by engulfing and removing bacteria, damaged cells, and other particles. CD68 helps macrophages carry out their role in the immune response. Why do pathologists test for CD68? Pathologists test …
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What is CD5?

CD5 is a protein normally found on the surface of specific immune cells, particularly certain types of lymphocytes (a kind of white blood cell). CD5 helps these immune cells communicate and interact within the immune system, especially in regulating immune responses and preventing autoimmune reactions. Why do pathologists test for CD5? Pathologists test for CD5 …
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What is CD3?

CD3 is a protein that is normally made by two types of specialized immune cells, T cells and NK cells. Most lymphomas that start from T and NK cells, including peripheral T cell lymphoma, anaplastic large cell lymphoma, and extranodal NK/T cell lymphoma, also make CD3. Two common tests used to look for CD3 in …
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Alveolar Rhabdomyosarcoma: Understanding Your Pathology Report

Alveolar rhabdomyosarcoma is a type of cancer that develops from cells that would normally become skeletal muscle. Skeletal muscle is the muscle that moves the arms, legs, and other parts of the body. It is a type of sarcoma, a cancer that begins in the body’s connective tissues. It is one of four main types …
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Embryonal Rhabdomyosarcoma: Understanding Your Pathology Report

Embryonal rhabdomyosarcoma is a type of cancer that develops from cells that would normally become skeletal muscle. Skeletal muscle is the muscle that moves the arms, legs, and other parts of the body. It is a type of sarcoma, a cancer that begins in the body’s connective tissues. Embryonal rhabdomyosarcoma is the most common type …
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Fibroma of the Oral Cavity: Understanding Your Pathology Report

A fibroma of the oral cavity is a common benign (non-cancerous) growth in the lining of the mouth. It is made of fibrous connective tissue, the same firm, supportive tissue found throughout the body. Rather than a true tumor, a fibroma is the mouth’s response to repeated irritation or injury: when the lining is injured …
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Anaplastic Thyroid Carcinoma: Understanding Your Pathology Report

Anaplastic thyroid carcinoma is a rare and highly aggressive type of thyroid cancer. It starts from follicular cells, the cells that normally make thyroid hormone, but over time, these cells change so much that they no longer look or behave like thyroid cells. For this reason, anaplastic thyroid carcinoma is sometimes called undifferentiated thyroid carcinoma. …
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Apocrine Cells: Definition

Apocrine cells are a type of glandular cell found in specific areas of the body, particularly in the skin. Under the microscope, apocrine cells are large and round with a visible central nucleolus (a small structure inside the nucleus). Their cytoplasm, the material surrounding the nucleus, often looks bright pink on a hematoxylin and eosin (H&E) …
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What is oncocytic?

The term oncocytic is used by pathologists to describe cells that appear bright pink under the microscope when stained with a routine stain called hematoxylin and eosin (H&E). These cells look pink because their cytoplasm (the body of the cell) is packed with mitochondria, which are small structures that produce energy for the cell. The …
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