pathology report

Respiratory Type Mucosa: Definition

Respiratory type mucosa is the specialized tissue found on the inner surface of the airways that carry air in and out of the lungs. This tissue is designed to protect the airways and help keep them clean by trapping dust, germs, and other particles before they reach the lungs. The word mucosa refers to a …
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What is a complete blood count (CBC)

A complete blood count, often shortened to CBC, is a common blood test that measures the number, size, and health of different types of blood cells. It provides important information about how well your bone marrow is working and how your body carries oxygen, fights infection, and controls bleeding. A CBC is often one of …
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Your pathology report for polycythemia vera

Polycythemia vera is a type of blood cancer called a myeloproliferative neoplasm. It is characterized by the bone marrow producing too many red blood cells. Many people also have increased white blood cells and or platelets. In most cases, polycythemia vera is caused by an acquired genetic change in a gene called JAK2 that sends …
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What is a myeloproliferative neoplasm?

A myeloproliferative neoplasm is a group of blood cancers that start in the bone marrow, the soft tissue inside your bones where new blood cells are made. In these conditions, the bone marrow produces too many mature blood cells. The extra cells may be red blood cells, white blood cells, or platelets, depending on the …
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What is a somatic mutation?

A somatic mutation is a change in a gene that occurs during a person’s lifetime in a specific group of cells. These mutations are not present at birth and are not passed down from parents. Instead, they develop in cells as they grow and divide. Somatic mutations are common in many types of cancer because …
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Variant Allele Frequency: Definition

Variant allele frequency (VAF) is a measurement used in the genetic testing of tumours. It describes how common a specific genetic change is within a tested tissue sample and is usually reported as a percentage. Tumours are often tested for genetic changes because these changes can explain why a cancer developed, how it may behave, …
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Your pathology report for essential thrombocythemia

Essential thrombocythemia (ET) is a type of blood cancer called a myeloproliferative neoplasm. This group of conditions starts in the bone marrow, the soft, spongy tissue inside your bones where blood cells are made. In essential thrombocythemia, the bone marrow produces too many platelets. Platelets are small cell fragments in the blood that help form …
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Your pathology report for myxopapillary ependymoma

Myxopapillary ependymoma is a type of glial tumor, meaning it develops from glial cells, which are support cells in the brain and spinal cord. It is considered a WHO grade 2 tumor. Although grade 2 tumors grow more slowly than high-grade tumors, myxopapillary ependymomas can still cause symptoms because they grow in tight spaces and …
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Anaplastic Meningioma: Understanding Your Pathology Report

Anaplastic meningioma is the most aggressive form of meningioma, classified as World Health Organization (WHO) grade 3. Meningiomas develop from meningothelial cells in the meninges, the thin layers of tissue that cover and protect the brain and spinal cord. Like all meningiomas, anaplastic meningiomas are dural-based tumors — they grow attached to the dura (the …
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Astrocytoma, IDH-Mutant : Understanding Your Pathology Report

Astrocytoma, IDH-mutant, is a type of brain tumor that develops from astrocytes, star-shaped glial cells that support nerve cells throughout the brain and spinal cord. It belongs to a larger group of tumors called diffuse gliomas. Diffuse gliomas are infiltrative, which means the tumor cells spread into the normal brain tissue around them and cannot …
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