In pathology, a tangentially sectioned tissue sample is one cut at an angle rather than straight across. When a sample is cut at an angle, the layers of tissue overlap in the thin slice placed on the microscope slide. This can make the sample difficult to interpret, and sometimes it prevents the pathologist from seeing …
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Background: Deep fibromatosis or desmoid tumour is a benign (non-cancerous) type of tumour that starts in connective tissue. It is considered locally aggressive because it can grow into surrounding tissues and organs. The tumour can also grow back if not completely removed. However, it will not metastasize (spread) to other body parts. Other names for …
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Squamous cell carcinoma is the most common type of cancer found in the oral cavity. It starts from squamous cells, which are thin, flat cells that form the surface lining of the mouth. The oral cavity includes the lips, front two-thirds of the tongue, inner cheeks (buccal mucosa), floor of the mouth, gums, retromolar trigone …
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Barrett esophagus is a condition where the normal lining of your esophagus is gradually replaced by a different type of cell. The esophagus is the tube that carries food and liquids from your mouth to your stomach. It is normally lined by squamous cells, which are flat, strong cells built to handle the wear and …
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Atypical endometrial hyperplasia (AEH) is a precancerous condition of the lining of the uterus, called the endometrium. In AEH, the endometrium becomes abnormally thick and the glandular cells that make up the endometrium start to grow in a crowded and irregular pattern. The cells also look abnormal under the microscope, which is why the word …
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Ductal adenocarcinoma is the most common type of pancreatic cancer. It starts from the cells that line the small tubes (ducts) inside the pancreas. These cells normally help transport digestive fluids made by the pancreas into the small intestine. In ductal adenocarcinoma, these cells begin to grow abnormally and invade the surrounding tissue. Over time, …
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High grade squamous intraepithelial lesion (HSIL) is a precancerous condition of the cervix caused by human papillomavirus (HPV). It is made up of squamous cells that have been infected and changed by the virus. These abnormal cells are found in the transformation zone, which is the part of the cervix where glandular cells are replaced …
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Background: Dedifferentiated liposarcoma is an aggressive type of cancer that typically starts in a deep location of the body, such as the abdomen. It is called dedifferentiated because it arises from within a similar but less aggressive type of cancer called well differentiated liposarcoma/atypical lipomatous tumour. The term ‘liposarcoma’ means that the cancer was originally …
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Pleomorphic adenoma is a non-cancerous tumour that most commonly arises in the salivary glands, especially the parotid gland, the largest salivary gland located near the ear and jaw. It is called “pleomorphic” because it contains a mix of different types of cells and tissue structures, including epithelial cells, myoepithelial cells, and stromal (connective tissue) elements. Pleomorphic …
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What is follicular lymphoma? Follicular lymphoma (FL) is a type of cancer that starts from specialized immune cells called B cells. FL is the second most common lymphoma to affect adults. Where in the body is follicular lymphoma found? FL can start anywhere in the body where B cells gather in large numbers. The most …
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